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How to get fromTampa to Durhamby bus, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

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There are 6 ways to get from Tampa to Durham by bus, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Tampa, fly, bus, line 700 bus

    best
    1. Take the bus from Marion Transit Center to Airport Rental Car Centerbus bus
    2. Fly from Tampa (TPA) to Raleigh-Durham International Airport (RDU)plane plane TPA - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    4. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    4h 59m
    $93–248

  2. Bus

    1. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus FlixBus 2421 / ...
    2. Take the bus from Orlando Bus Station to Raleigh Bus Stationbus bus FlixBus N2472
    15h 15m
    $105–180

  3. Train (Amtrak)

    1. Take the train from Tampa to Carytrain train Floridian
    16h 53m
    $223–470

  4. Drive 646.1 mi

    1. Drive from Tampa to Durhamcar car 646.1 mi
    11h 38m
    $118–171

  5. Bus to Sarasota–Bradenton International Airport, fly

    1. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Raleigh-Durham International Airport (RDU)plane plane SRQ - RDU
    7h 31m
    $128–675

  6. Train to Orlando, fly

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Raleigh-Durham International Airport (RDU)plane plane MCO - RDU
    7h
    $93–349

Tampa to Durham by bus

Calendar5Weekly Buses
Duration15h 15mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

Map of how to get from Tampa to Durham.ExpandLaunch map view
  • Distance: 614.7 mi
  • Duration: 4h 59m

What companies run services between Tampa, FL, USA and Durham, NC, USA?

You can take a bus from Tampa Bus Station to Durham via Orlando Bus Station and Raleigh Bus Station in around 15h 15m. Alternatively, Amtrak operates a train from Tampa to Cary once daily. Tickets cost $210–460 and the journey takes 15h 35m.

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Train operators
Bus operators

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