There are 5 ways to get from Tampa to Florence by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Tampa (TPA) to Florence Regional Airport (FLO)plane TPA - FLO
6h 31m$82–405Bus
- Take the bus from Tampa Bus Station to Orlando Bus Stationbus FlixBus 2421 / ...
- Take the bus from Orlando Bus Station to Florencebus FlixBus N2472
11h 11m$98–172Train (Amtrak)
- Take the train from Tampa to Kissimmee Amtrak Stationtrain Floridian
- Take the train from Kissimmee Amtrak Station to Florence Stationtrain Silver Meteor
12h 43m$184–389Drive 497 mi
- Drive from Tampa to Florencecar 497 mi
8h 29m$91–131Train, bus
- Take the train from Tampa to Jacksonvilletrain
- Take the bus from Jacksonville to Sumter Bus Stopbus
- Take the bus from Sumter Bus Stop to Florence Bus Stationbus
15h 23m$129–262
Tampa to Florence by train (Amtrak)
Questions & Answers
The cheapest way to get from Tampa to Florence is to drive which costs $90 - $140 and takes 8h 29m.
The fastest way to get from Tampa to Florence is to fly which takes 6h 31m and costs $80 - $410.
No, there is no direct bus from Tampa station to Florence. However, there are services departing from Tampa Bus Station and arriving at Florence via Orlando Bus Station. The journey, including transfers, takes approximately 11h 11m.
No, there is no direct train from Tampa to Florence station. However, there are services departing from Tampa and arriving at Florence Station via Kissimmee Amtrak Station. The journey, including transfers, takes approximately 12h 43m.
The distance between Tampa and Florence is 475 miles. The road distance is 499.9 miles.
The best way to get from Tampa to Florence without a car is to bus which takes 11h 11m and costs $95 - $180.
It takes approximately 6h 31m to get from Tampa to Florence, including transfers.
Tampa to Florence bus services, operated by Flixbus USA, depart from Tampa Bus Station.
Tampa to Florence train services, operated by Amtrak, depart from Tampa station.
The best way to get from Tampa to Florence is to fly which takes 6h 31m and costs $80 - $410. Alternatively, you can bus, which costs $95 - $180 and takes 11h 11m, you could also train, which costs $180 - $390 and takes 12h 43m.
What companies run services between Tampa, FL, USA and Florence, SC, USA?
American Airlines flies from Tampa (TPA) to Florence Regional Airport (FLO) twice daily. Alternatively, you can take a bus from Tampa Bus Station to Florence via Orlando Bus Station and Florence in around 11h 11m.
- Website
- aa.com
Flights from Tampa to Florence Regional Airport via Charlotte
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $70–390
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Tampa to Kissimmee Amtrak Station
- Ave. Duration
- 1h 18m
- Frequency
- Once daily
- Estimated price
- $23–50
- Website
- https://www.amtrak.com/home.html
Train from Kissimmee Amtrak Station to Florence Station
- Ave. Duration
- 10h 25m
- Frequency
- Once daily
- Estimated price
- $160–340
- Website
- https://www.amtrak.com/home.html
Train from Tampa to Jacksonville
- Ave. Duration
- 5h 24m
- Frequency
- Once daily
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Tampa Bus Station to Orlando Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- 5 times a day
- Estimated price
- $13–23
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Florence
- Ave. Duration
- 8h 25m
- Frequency
- 5 times a week
- Estimated price
- $70–130
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Tampa Bus Station to Orlando Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
Bus from Jacksonville to Sumter Bus Stop
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Sumter Bus Stop to Florence Bus Station
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $6–12
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Tampa to Florence bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Tampa to Florence train services, operated by Amtrak, arrive at Kissimmee Amtrak Station.
Yes, the driving distance between Tampa to Florence is 500 miles. It takes approximately 8h 29m to drive from Tampa to Florence.
Book your Tampa to Florence train tickets online with Omio.
Book your Tampa to Florence bus tickets online with Omio.
There are 49+ hotels available in Florence.