There are 9 ways to get from Tampa to Florida Keys by plane, bus, bus (Flixbus, Greyhound), train, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Tampa to Key West International Airport, bus
best- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
5h 55m$154–646Bus
cheapest- Take the bus from Tampa Bus Station to Miami Airport Stationbus FlixBus 2421 / ...
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
12h 10m$67–129Train, bus
- Take the train from Tampa to Hollywood Amtrak Stationtrain Floridian
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
12h 20m$105–208Drive 375.4 mi
- Drive from Tampa to Florida Keyscar 375.4 mi
7h 44m$69–99Line 300 bus to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport, bus
- Take the bus from Marion Transit Parking Lot to Psta 34Th St Complex - Shelter - Dbus
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane PIE - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
6h 22m$117–339Fly Tampa to Miami International Airport, shuttle
- Fly from Tampa (TPA) to Miami International Airport (MIA)plane TPA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
8h 24m$954–1,286Fly Tampa to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane TPA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
8h 49m$284–856Train to Orlando, fly to Key West International Airport
- Take the train from Tampa to Kissimmee Amtrak Stationtrain
- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
7h 58m$171–799Bus, shuttle
- Take the bus from University of South Florida - 3801 USF Holly Dr to Miami Airportbus Tallahassee
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
13h 25m$221–318
Tampa to Florida Keys by bus and foot
Questions & Answers
The cheapest way to get from Tampa to Florida Keys is to bus which costs $65 - $130 and takes 12h 10m.
The fastest way to get from Tampa to Florida Keys is to fly and bus which takes 5h 55m and costs $150 - $650.
No, there is no direct bus from Tampa station to Florida Keys. However, there are services departing from Tampa Bus Station and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 12h 10m.
The distance between Tampa and Florida Keys is 274 miles. The road distance is 377.6 miles.
The best way to get from Tampa to Florida Keys without a car is to bus which takes 12h 10m and costs $65 - $130.
It takes approximately 5h 55m to get from Tampa to Florida Keys, including transfers.
Tampa to Florida Keys bus services, operated by Flixbus USA, depart from Tampa Bus Station.
Tampa to Florida Keys bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Tampa to Florida Keys is 378 miles. It takes approximately 7h 44m to drive from Tampa to Florida Keys.
There are 972+ hotels available in Florida Keys.
What companies run services between Tampa, FL, USA and Florida Keys, FL, USA?
You can take a bus from Tampa Bus Station to Florida Keys via Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 12h 10m.
- Website
- aa.com
Flights from Tampa to Miami International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $40–280
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 10m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $35–230
- Website
- flybreeze.com
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 18m
- When
- Thursday, Sunday, Monday, Wednesday, Friday, and Tuesday
- Estimated price
- $75–550
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $100–550
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $65–650
- Website
- allegiantair.com
Flights from Saint Petersburg–Clearwater International Airport to Key West International Airport
- Ave. Duration
- 1h 4m
- When
- Wednesday, Thursday, Sunday, Monday, Friday, and Saturday
- Estimated price
- $35–240
- Website
- southwest.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $40–310
- Website
- jetblue.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $40–310
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Tampa to Hollywood Amtrak Station
- Ave. Duration
- 5h 3m
- Frequency
- Once daily
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
Train from Tampa to Kissimmee Amtrak Station
- Ave. Duration
- 1h 18m
- Frequency
- Once daily
- Estimated price
- $24–50
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Tampa Bus Station to Miami Airport Station
- Ave. Duration
- 6h
- Frequency
- 5 times a day
- Estimated price
- $45–75
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Tampa Bus Station to Miami Airport Station
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1 727-540-1900
- [email protected]
- Website
- psta.net
Bus from Marion Transit Parking Lot to Psta 34Th St Complex - Shelter - D
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- $3
- Schedules at
- psta.net
- Adult
- $3
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from University of South Florida - 3801 USF Holly Dr to Miami Airport
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.redcoachusa.com
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