Rome2Rio

How to get fromTampa to Great Smoky Mountainsby car, plane, bus, or train

Find Transport to Great Smoky Mountains

See all options

There are 9 ways to get from Tampa to Great Smoky Mountains by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Mcghee Tyson Airport, drive

    best
    1. Drive from Tampa to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    5h 29m
    $139–694

  2. Fly Saint Petersburg–Clearwater International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Asheville Regional Airport (AVL)plane plane PIE - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    6h 10m
    $79–377

  3. Bus, drive

    1. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    20h 38m
    $135–269

  4. Train, bus, drive

    1. Take the train from Tampa to Carytrain train
    2. Take the train from Cary to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    24h 14m
    $291–592

  5. Drive 621.9 mi

    1. Drive from Tampa to Great Smoky Mountainscar car 621.9 mi
    11h 35m
    $114–164

  6. Fly Saint Petersburg–Clearwater International Airport to Mcghee Tyson Airport, drive

    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Mcghee Tyson Airport (TYS)plane plane PIE - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    5h 58m
    $125–671

  7. Fly Tampa to Greenville–Spartanburg International Airport, drive

    1. Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane plane TPA - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    6h 35m
    $116–367

  8. Fly Tampa to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Tampa (TPA) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane TPA - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    7h 19m
    $227–657

  9. Train to Orlando, fly to Mcghee Tyson Airport, drive

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 23m
    $138–671

Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights

Calendar11Weekly Planes
Duration1h 38mAverage Duration
Ticket$110Cheapest Price
See schedules

Questions & Answers

Map of how to get from Tampa to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 675.9 mi
  • Duration: 5h 29m

What companies run services between Tampa, FL, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Tampa to Great Smoky Mountains. However, you can drive to Orlando-Sanford-Airport-SFB airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Tampa Bus Station to Great Smoky Mountains via Orlando Bus Station, Charlotte Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 20h 38m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound