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How to get fromTampa to Key West, FLby bus, plane, ferry, train, shuttle, car, or bus (Flixbus, Greyhound)

Find Transport to Key West, FL

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There are 11 ways to get from Tampa to Key West, FL by bus, plane, ferry, train, shuttle, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Tampa, fly to Key West International Airport

    best
    1. Take the bus from Marion Transit Center to Airport Rental Car Facilitybus bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    4h 18m
    $147–482

  2. Drive 392.3 mi

    cheapest
    1. Drive from Tampa to Key West, FLcar car 392.3 mi
    8h 11m
    $72–104

  3. Bus, ferry

    1. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    11h 1m
    $153–171

  4. Train, bus, shuttle

    1. Take the train from Tampa to Delray Beach Amtraktrain train
    2. Take the train from Delray Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take a shuttle bus from Big Pine Key, FL to Key West, FLshuttle bus
    12h 16m
    $198–311

  5. Bus, shuttle

    1. Take the bus from Tampa USF to Miami Airportbus bus Tallahassee–Miami via Tampa / ...
    2. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus To the Keys
    12h 17m
    $244–344

  6. Line 300 bus to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport

    1. Take the bus from Marion Transit Parking Lot to Psta 34Th St Complex - Shelter - Dbus bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    4h 45m
    $115–335

  7. Drive to Orlando Sanford, fly to Key West International Airport

    1. Drive from Tampa to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    4h 31m
    $129–368

  8. Bus to Sarasota–Bradenton International Airport, fly to Key West International Airport

    1. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW)plane plane SRQ - EYW
    7h 54m
    $586–1,008

  9. Fly Tampa to Miami International Airport, shuttle

    1. Fly from Tampa (TPA) to Miami International Airport (MIA)plane plane TPA - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    7h 54m
    $922–1,302

  10. Train to Orlando, fly to Key West International Airport

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    6h 22m
    $168–794

  11. Bus

    1. Take the bus from Tampa Bus Station to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to Whitehead & Eatonbus bus Lks
    13h 24m
    $84–148

Tampa to Key West, FL by train, bus, and shuttle

Calendar7Weekly Services
Duration12h 16mAverage Duration
Ticket$198Cheapest Price
See schedules

Questions & Answers

Map of how to get from Tampa to Key West, FL.ExpandLaunch map view
  • Distance: 254.6 mi
  • Duration: 4h 18m

What companies run services between Tampa, FL, USA and Key West, FL, USA?

You can take a bus from Tampa Bus Station to Whitehead & Eaton via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 13h 24m.

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Train operators
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