There are 9 ways to get from Tampa to Key West, FL by bus, plane, ferry, train, shuttle, bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Tampa, fly
best- Take the bus from Marion Transit Center to Airport Rental Car Centerbus
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
4h 14m$132–332Bus
cheapest- Take the bus from Tampa Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to Whitehead & Eatonbus Lks
13h 24m$64–128Bus, ferry
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus FlixBus 2421
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
11h 36m$153–170Train, bus, shuttle
- Take the train from Tampa to Delray Beach Amtraktrain
- Take the train from Delray Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take a shuttle bus from Big Pine Key, FL to Key West, FL
12h 16m$169–281Bus, shuttle
- Take the bus from University of South Florida - 3801 USF Holly Dr to Miami Airportbus Tallahassee
- Take a shuttle bus from Miami, FL - International Airport to Key West, FLTo the Keys
12h 19m$244–344Line 300 bus to Saint Petersburg–Clearwater International Airport, fly
- Take the bus from Marion Transit Parking Lot to Psta 34Th St Complex - Shelter - Dbus
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane PIE - EYW
4h 43m$110–335Bus to Sarasota–Bradenton International Airport, fly
- Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus
- Fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW)plane SRQ - EYW
8h 9m$141–479Train to Orlando, fly
- Take the train from Tampa to Kissimmee Amtrak Stationtrain
- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
6h 29m$164–789Drive 392.3 mi
- Drive from Tampa to Key West, FLcar 392.3 mi
8h 11m$72–104
Tampa to Key West, FL by train, bus, and shuttle
Questions & Answers
The cheapest way to get from Tampa to Key West, FL is to bus which costs $60 - $130 and takes 13h 24m.
The fastest way to get from Tampa to Key West, FL is to bus and fly which takes 4h 14m and costs $130 - $340.
No, there is no direct bus from Tampa station to Key West, FL. However, there are services departing from Tampa Bus Station and arriving at Whitehead & Eaton via Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 13h 24m.
The distance between Tampa and Key West, FL is 257 miles. The road distance is 394.6 miles.
The best way to get from Tampa to Key West, FL without a car is to bus and ferry which takes 11h 36m and costs $150 - $170.
It takes approximately 4h 14m to get from Tampa to Key West, FL, including transfers.
Tampa to Key West, FL bus services, operated by Flixbus USA, depart from Tampa Bus Station.
Tampa to Key West, FL bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Tampa to Key West, FL is 395 miles. It takes approximately 8h 11m to drive from Tampa to Key West, FL.
There are 971+ hotels available in Key West, FL.
What companies run services between Tampa, FL, USA and Key West, FL, USA?
You can take a bus from Tampa Bus Station to Whitehead & Eaton via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 13h 24m.
- Website
- aa.com
Flights from Tampa to Key West International Airport via Miami
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- $35–250
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Miami
- Ave. Duration
- 3h 11m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $55–370
Flights from Sarasota–Bradenton International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $130–600
Flights from Orlando to Key West International Airport via Miami
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- $35–230
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Tampa to Delray Beach Amtrak
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $55–130
- Website
- Amtrak
Train from Tampa to Kissimmee Amtrak Station
- Ave. Duration
- 1h 18m
- Frequency
- Once daily
- Estimated price
- $19–45
- Website
- Amtrak
- Phone
- +1 813-254-4278
- Website
- HART
Bus from Marion Transit Center to Airport Rental Car Center
- Ave. Duration
- 32 min
- Frequency
- Every 30 minutes
- Estimated price
- $1–2
- Website
- HART
- Phone
- +1 239-463-5733
- Website
- Key West Express
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- Key West Express
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