Rome2Rio

How to get fromTampa to Knoxville Airport (TYS)by plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to Knoxville Airport (TYS)

See all options

There are 9 ways to get from Tampa to Knoxville Airport (TYS) by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Tampa

    best
    1. Fly from Tampa (TPA) to Mcghee Tyson Airport (TYS)plane plane TPA - TYS
    5h 13m
    $132–752

  2. Drive 632.7 mi

    cheapest
    1. Drive from Tampa to Knoxville Airport (TYS)car car 632.7 mi
    11h 12m
    $116–167

  3. Bus via Knoxville

    1. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    37h 13m
    $367–553

  4. Train, bus

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    2. Take the train from Kissimmee Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    38h 57m
    $536–991

  5. Drive to Orlando Sanford, fly

    1. Drive from Tampa to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    3h 37m
    $139–728

  6. Line 300 bus to Saint Petersburg–Clearwater International Airport, fly

    1. Take the bus from Marion Transit Parking Lot to Psta 34Th St Complex - Shelter - Dbus bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Mcghee Tyson Airport (TYS)plane plane PIE - TYS
    4h 6m
    $125–705

  7. Bus to Sarasota–Bradenton International Airport, fly

    1. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Mcghee Tyson Airport (TYS)plane plane SRQ - TYS
    5h 43m
    $192–1,120

  8. Train to Orlando, fly

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    5h 32m
    $137–704

  9. Bus

    1. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    37h 24m
    $342–493

Tampa (TPA) to Mcghee Tyson Airport (TYS) flights

Calendar82Weekly Planes
Duration4h 8mAverage Duration
Ticket$131Cheapest Price
See schedules

Questions & Answers

Map of how to get from Tampa to Knoxville Airport (TYS).ExpandLaunch map view
  • Distance: 557 mi
  • Duration: 5h 13m

What companies run services between Tampa, FL, USA and Knoxville Airport (TYS), USA?

Delta, Southwest Airlines, and American Airlines fly from Tampa (TPA) to Mcghee Tyson Airport (TYS) every 2 hours. Alternatively, you can take a bus from Tampa Bus Station to Knoxville Airport (TYS) via Orlando Bus Station, New York City Chinatown, New York, and Knoxville in around 37h 13m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers