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How to get fromTampa to Lake Cityby plane, car, bus, taxi, train (Amtrak), or train

Find Transport to Lake City

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There are 5 ways to get from Tampa to Lake City by plane, car, bus, taxi, train (Amtrak), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Tampa, drive

    best
    1. Fly from Tampa (TPA) to Myrtle Beach (MYR)plane plane TPA - MYR
    2. Drive from Myrtle Beach (MYR) to Lake Citycar car
    4h 49m
    $88–278

  2. Bus, taxi

    1. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Florencebus bus
    3. Take the taxi from Florence to Lake Citytaxi taxi
    11h 43m
    $162–243

  3. Train (Amtrak)

    1. Take the train from Tampa to Jacksonvilletrain train Floridian
    2. Take the train from Jacksonville to Kingstree Stationtrain train Silver Meteor
    12h
    $215–417

  4. Drive 488.3 mi

    1. Drive from Tampa to Lake Citycar car 488.3 mi
    8h 24m
    $90–129

  5. Train to Orlando, fly, drive

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Myrtle Beach (MYR)plane plane MCO - MYR
    3. Drive from Myrtle Beach (MYR) to Lake Citycar car
    6h 50m
    $133–341

Tampa (TPA) to Myrtle Beach (MYR) flights

Calendar31Weekly Planes
Duration3h 24mAverage Duration
Ticket$64Cheapest Price
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Questions & Answers

Map of how to get from Tampa to Lake City.ExpandLaunch map view
  • Distance: 518.1 mi
  • Duration: 4h 49m

What companies run services between Tampa, FL, USA and Lake City, SC, USA?

You can take a train from Tampa to Lake City via Jacksonville and Kingstree Station in around 12h.

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