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How to get fromTampa to Mayo Clinicby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 6 ways to get from Tampa to Mayo Clinic by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Tampa (TPA) to Rochester (RST)plane plane TPA - RST
    8h 36m
    $123–592

  2. Bus

    1. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    34h 58m
    $269–461

  3. Train, bus via Madison

    1. Take the train from Tampa to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    2d 3h
    $659–1,315

  4. Drive 1,455.8 mi

    1. Drive from Tampa to Mayo Cliniccar car 1,455.8 mi
    24h 45m
    $266–384

  5. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Tampa (TPA) to Minneapolis–Saint Paul International Airport (MSP)plane plane TPA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 55m
    $544–1,154

  6. Train, bus

    1. Take the train from Tampa to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochester, MNbus bus
    2d 4h
    $742–1,495

Tampa to Mayo Clinic by train, bus, and foot

Calendar7Weekly Services
Duration2d 4hAverage Duration
Ticket$742Cheapest Price
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Questions & Answers

Map of how to get from Tampa to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,250.3 mi
  • Duration: 8h 36m

What companies run services between Tampa, FL, USA and Mayo Clinic, MN, USA?

American Airlines, Delta, and two other airlines fly from Tampa (TPA) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Tampa Bus Station to Mayo Clinic via Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 34h 58m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

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