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How to get fromTampa to Mayo Clinic Floridaby train (Amtrak), bus (Flixbus, Greyhound), car, plane, taxi, or bus

Find Transport to Mayo Clinic Florida

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There are 5 ways to get from Tampa to Mayo Clinic Florida by train (Amtrak), bus (Flixbus, Greyhound), car, plane, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Tampa to Jacksonvilletrain train Floridian
    5h 57m
    $131–227

  2. Drive 200.8 mi

    cheapest
    1. Drive from Tampa to Mayo Clinic Floridacar car 200.8 mi
    3h 51m
    $37–53

  3. Bus

    1. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus FlixBus 2421 / ...
    2. Take the bus from Orlando Bus Station to Jacksonvillebus bus FlixBus 2433 / ...
    6h 39m
    $44–78

  4. Fly from Tampa, taxi

    1. Fly from Tampa (TPA) to Jacksonville (JAX)plane plane TPA - JAX
    2. Take the taxi from Jacksonville-Airport-JAX to Mayo Clinic Floridataxi taxi
    5h 48m
    $392–742

  5. Bus to Sarasota–Bradenton International Airport, fly, taxi

    1. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Jacksonville (JAX)plane plane SRQ - JAX
    3. Take the taxi from Jacksonville-Airport-JAX to Mayo Clinic Floridataxi taxi
    8h 25m
    $172–611

Tampa (TPA) to Jacksonville (JAX) flights

Calendar111Weekly Planes
Duration4h 44mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Tampa to Mayo Clinic Florida.ExpandLaunch map view
  • Distance: 259.8 mi
  • Duration: 5h 57m

What companies run services between Tampa, FL, USA and Mayo Clinic Florida, FL, USA?

Amtrak operates a train from Tampa to Jacksonville once daily. Tickets cost $75–160 and the journey takes 5h 24m. Alternatively, you can take a bus from Tampa Bus Station to Mayo Clinic Florida via Orlando Bus Station, Jacksonville, JRTC Bay M, and Beach Blvd + Hodges Blvd in around 6h 39m.

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