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How to get fromTampa to Santa Anaby plane, bus (Greyhound), train (Amtrak), car, train, or bus (Flixbus, Greyhound, Amtrak)

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There are 8 ways to get from Tampa to Santa Ana by plane, bus (Greyhound), train (Amtrak), car, train, or bus (Flixbus, Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Tampa (TPA) to John Wayne Airport Orange County (SNA)plane plane TPA - SNA
    8h 25m
    $231–687

  2. Fly to Long Beach Airport

    cheapest
    1. Fly from Tampa (TPA) to Long Beach Airport (LGB)plane plane TPA - LGB
    11h 24m
    $187–760

  3. Bus via Ciudad Juárez

    1. Take the bus from Tampa Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Houston Bus Stationbus bus
    3. Take the bus from Houston, TX - Houston Airline Dr to El Paso, TX - Tornado Bus Cobus bus
    4. Take the bus from El Paso to Santa Anabus bus
    2d 6h
    $392–737

  4. Train (Amtrak)

    1. Take the train from Tampa to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    3d 13h
    $1,295–2,689

  5. Drive 2,428.4 mi

    1. Drive from Tampa to Santa Anacar car 2,428.4 mi
    40h 36m
    $444–641

  6. Fly to Los Angeles International Airport, train

    1. Fly from Tampa (TPA) to Los Angeles International Airport (LAX)plane plane TPA - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    9h 24m
    $230–838

  7. Fly to San Diego International Airport, train

    1. Fly from Tampa (TPA) to San Diego International Airport (SAN)plane plane TPA - SAN
    2. Take the train from San Diego to Santa Anatrain train
    10h 8m
    $424–1,022

  8. Bus

    1. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to Santa Anabus bus
    2d 12h
    $445–827

Tampa to Santa Ana by train (Amtrak)

Calendar7Weekly Trains
Duration3d 13hAverage Duration
Ticket$1,295Cheapest Price
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Questions & Answers

Map of how to get from Tampa to Santa Ana.ExpandLaunch map view
  • Distance: 2,137.3 mi
  • Duration: 8h 25m

What companies run services between Tampa, FL, USA and Santa Ana, CA, USA?

Southwest Airlines, American Airlines, and three other airlines fly from Tampa (TPA) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a bus from Tampa Bus Station to Santa Ana via Tallahassee, Houston Bus Station, Magnolia Park Transit Center WB, Theater District Capitol WB, Houston, TX - Houston Airline Dr, El Paso, TX - Tornado Bus Co, and El Paso in around 2d 6h.

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