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How to get fromTampa to Santa Anaby plane, bus (Greyhound), train (Amtrak), car, or train

Find Transport to Santa Ana

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There are 8 ways to get from Tampa to Santa Ana by plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Tampa (TPA) to John Wayne Airport Orange County (SNA)plane plane TPA - SNA
    8h 45m
    $201–787

  2. Fly to Los Angeles International Airport, train

    cheapest
    1. Fly from Tampa (TPA) to Los Angeles International Airport (LAX)plane plane TPA - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    9h 44m
    $138–485

  3. Bus via El Monte

    1. Take the bus from Tampa Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Houston Bus Stationbus bus
    3. Take the bus from Houston Bus Station to El Paso Bus Stationbus bus
    4. Take the bus from El Paso to El Montebus bus
    5. Take the bus from El Monte to Santa Anabus bus
    2d 5h
    $448–670

  4. Train (Amtrak)

    1. Take the train from Tampa to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    3d 13h
    $2,192–3,422

  5. Drive  2,438.1 mi

    1. Drive from Tampa to Santa Anacar car 2,438.1 mi
    40h 12m
    $417–602

  6. Fly to San Diego International Airport, train

    1. Fly from Tampa (TPA) to San Diego International Airport (SAN)plane plane TPA - SAN
    2. Take the train from San Diego to Santa Anatrain train
    10h 21m
    $184–687

  7. Fly to Long Beach Airport

    1. Fly from Tampa (TPA) to Long Beach Airport (LGB)plane plane TPA - LGB
    11h 55m
    $157–659

  8. Bus

    1. Take the bus from Tampa Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Houston Bus Stationbus bus
    3. Take the bus from Houston, TX - Houston Airline Dr to El Paso, TX - Tornado Bus Cobus bus
    4. Take the bus from El Paso to Santa Anabus bus
    2d 6h
    $457–631

Tampa to Santa Ana by bus and foot

Calendar7Weekly Services
Duration2d 5hAverage Duration
Ticket$448Cheapest Price
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Comparing Your Travel Options

Map of how to get from Tampa to Santa Ana.ExpandLaunch map view
  • Distance: 2,137.8 mi
  • Duration: 8h 45m

What companies run services between Tampa, FL, USA and Santa Ana, CA, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Tampa (TPA) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a bus from Tampa Bus Station to Santa Ana via Tallahassee, Houston Bus Station, El Paso Bus Station, El Paso, El Monte, and El Monte in around 2d 5h.

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