What is the cheapest way to get from Tampa to South Knoxville?

The cheapest way to get from Tampa to South Knoxville is to drive which costs $110 - $170 and takes 11h 27m.

What is the fastest way to get from Tampa to South Knoxville?

The fastest way to get from Tampa to South Knoxville is to drive and fly which takes 3h 56m and costs $180 - $750.

How far is it from Tampa to South Knoxville?

The distance between Tampa and South Knoxville is 573 miles. The road distance is 647.5 miles.

How long does it take to get from Tampa to South Knoxville?

It takes approximately 5h 32m to get from Tampa to South Knoxville, including transfers.

Can I drive from Tampa to South Knoxville?

Yes, the driving distance between Tampa to South Knoxville is 647 miles. It takes approximately 11h 27m to drive from Tampa to South Knoxville.

Where can I stay near South Knoxville?

There are 286+ hotels available in South Knoxville.

Tampa to South Knoxville - 7 ways to travel via train, plane, bus, and shuttle

There are 7 ways to get from Tampa to South Knoxville by plane, bus, shuttle, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly from Tampa
best
1. Fly from Tampa (TPA) to Mcghee Tyson Airport (TYS)plane TPA - TYS
5h 32m
$177–772
Drive 643.7 mi
cheapest
1. Drive from Tampa to South Knoxvillecar 643.7 mi
11h 27m
$118–170
Bus, shuttle, drive
1. Take the bus from Tampa Bus Station to Orlando Bus Stationbus
2. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus
3. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus
4. Take a shuttle bus from Boone to Black Bear Resortshuttle
5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle
6. Drive from Hot Springs to South Knoxvillecar
21h 33m
$447–555
Drive to Orlando Sanford, fly
1. Drive from Tampa to Orlando-Sanford-Airport-SFBcar
2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane SFB - TYS
3h 56m
$184–748
Line 300 bus to Saint Petersburg–Clearwater International Airport, fly
1. Take the bus from Marion Transit Parking Lot to Psta 34Th St Complex - Shelter - Dbus
2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Mcghee Tyson Airport (TYS)plane PIE - TYS
4h 25m
$170–725
Bus to Sarasota–Bradenton International Airport, fly
1. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus
2. Fly from Sarasota–Bradenton International Airport (SRQ) to Mcghee Tyson Airport (TYS)plane SRQ - TYS
6h 2m
$217–940
Train to Orlando, fly
1. Take the train from Tampa to Kissimmee Amtrak Stationtrain
2. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane MCO - TYS
5h 50m
$182–725

Tampa (TPA) to Mcghee Tyson Airport (TYS) flights

82Weekly Planes

4h 8mAverage Duration

$122Cheapest Price

See schedules

Questions & Answers

Map of how to get from Tampa to South Knoxville.

Launch map view

Distance: 569.4 mi
Duration: 5h 32m

What companies run services between Tampa, FL, USA and South Knoxville, TN, USA?

Delta, Southwest Airlines, and American Airlines fly from Tampa (TPA) to Mcghee Tyson Airport (TYS) every 2 hours.

Airlines

Train operators

Bus operators

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