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How to get fromTampa to St. Louisby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

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There are 6 ways to get from Tampa to St. Louis by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Tampa

    best
    1. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    4h 53m
    $105–555

  2. Bus

    1. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus FlixBus N2467
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    22h 5m
    $175–274

  3. Train (Amtrak)

    1. Take the train from Tampa to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    46h 42m
    $1,138–1,756

  4. Drive  1,007.7 mi

    1. Drive from Tampa to St. Louiscar car 1,007.7 mi
    16h 36m
    $173–249

  5. Bus to Sarasota–Bradenton International Airport, fly

    1. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Lambert–St. Louis International Airport (STL)plane plane SRQ - STL
    6h 16m
    $124–620

  6. Train to Orlando, fly

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane plane MCO - STL
    7h 9m
    $198–562

Tampa to St. Louis by bus

Calendar5Weekly Buses
Duration22h 5mAverage Duration
Ticket$175Cheapest Price
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Comparing Your Travel Options

Map of how to get from Tampa to St. Louis.ExpandLaunch map view
  • Distance: 893.2 mi
  • Duration: 4h 53m

What companies run services between Tampa, FL, USA and St. Louis, MO, USA?

Southwest Airlines and Delta fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL) every 2 hours. Alternatively, you can take a bus from Tampa Bus Station to St Louis Bus Station via Atlanta Bus Station in around 22h 5m.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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Need to know: Greyhound

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