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How to get fromTampa to St. Louisby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Find Transport to St. Louis

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There are 7 ways to get from Tampa to St. Louis by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Tampa to Lambert–St. Louis International Airport

    best
    1. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    4h 53m
    $425–2,005

  2. Line 300 bus to Saint Petersburg–Clearwater International Airport, fly to Midamerica St. Louis Airport, train

    cheapest
    1. Take the bus from Marion Transit Parking Lot to Psta 34Th St Complex - Shelter - Dbus bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Midamerica St. Louis Airport (BLV)plane plane PIE - BLV
    3. Take the train from SHILOH-SCOTT station to CIVIC CENTER stationtrain train
    5h 47m
    $111–467

  3. Bus

    1. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus FlixBus N2467
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    20h 55m
    $149–242

  4. Train (Amtrak)

    1. Take the train from Tampa to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    46h 42m
    $537–1,197

  5. Drive  1,007.7 mi

    1. Drive from Tampa to St. Louiscar car 1,007.7 mi
    16h 36m
    $184–266

  6. Bus to Sarasota–Bradenton International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Lambert–St. Louis International Airport (STL)plane plane SRQ - STL
    6h 51m
    $185–921

  7. Train to Orlando, fly to Lambert–St. Louis International Airport

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane plane MCO - STL
    7h 4m
    $206–541

Tampa to St. Louis by bus

Calendar7Weekly Buses
Duration20h 55mAverage Duration
Ticket$149Cheapest Price
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Comparing Your Travel Options

Map of how to get from Tampa to St. Louis.ExpandLaunch map view
  • Distance: 893.2 mi
  • Duration: 4h 53m

What companies run services between Tampa, FL, USA and St. Louis, MO, USA?

Southwest Airlines and Delta fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Tampa Bus Station to St Louis Bus Station via Atlanta Bus Station in around 20h 55m.

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