There are 11 ways to get from Tennessee to Mayo Clinic by plane, bus, train, car, bus (Greyhound, Flixbus), or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Mcghee Tyson Airport to Rochester
best- Fly from Mcghee Tyson Airport (TYS) to Rochester (RST)plane TYS - RST
6h 26m$143–577Fly Nashville to Rochester
cheapest- Fly from Nashville (BNA) to Rochester (RST)plane BNA - RST
6h 55m$88–522Bus, train via Milwaukee
- Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus
- Take the train from Carbondale to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee to Rochesterbus
20h 45m$204–382Bus, train
- Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus
- Take the train from Carbondale to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochesterbus
22h 32m$240–512Drive 755.8 mi
- Drive from Nashville to Mayo Cliniccar 755.8 mi
13h 14m$138–200Fly Mcghee Tyson Airport to Minneapolis–Saint Paul International Airport, bus
- Fly from Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP)plane TYS - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
5h 39m$219–719Fly Memphis to Rochester
- Fly from Memphis (MEM) to Rochester (RST)plane MEM - RST
7h 49m$102–591Fly Nashville to Minneapolis–Saint Paul International Airport, bus
- Fly from Nashville (BNA) to Minneapolis–Saint Paul International Airport (MSP)plane BNA - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
6h 32m$454–1,154Fly Memphis to Minneapolis–Saint Paul International Airport, bus
- Fly from Memphis (MEM) to Minneapolis–Saint Paul International Airport (MSP)plane MEM - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
6h 40m$163–703Bus
- Take the bus from Nashville Bus Station to Chicago Bus Stationbus
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Rochesterbus
20h 56m$147–262Bus via Lafayette
- Take the bus from Nashville to Lafayette Amtrak Stationbus
- Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Rochesterbus
21h 29m$151–247
Tennessee to Mayo Clinic by bus, train, and foot
Questions & Answers
The cheapest way to get from Tennessee to Mayo Clinic is to drive which costs $130 - $200 and takes 13h 14m.
The fastest way to get from Tennessee to Mayo Clinic is to fly and bus which takes 5h 39m and costs $210 - $750.
No, there is no direct bus from Tennessee to Mayo Clinic. However, there are services departing from Central 4Th Ave - Bay 13 and arriving at Rochester via Nashville Bus Station, W Jackson Blvd, after S Clinton St and Madison. The journey, including transfers, takes approximately 20h 56m.
The distance between Tennessee and Mayo Clinic is 744 miles. The road distance is 760.2 miles.
The best way to get from Tennessee to Mayo Clinic without a car is to bus and train via Milwaukee which takes 20h 45m and costs $200 - $390.
It takes approximately 6h 26m to get from Tennessee to Mayo Clinic, including transfers.
Tennessee to Mayo Clinic bus services, operated by Greyhound USA, depart from Nashville Bus Station.
The best way to get from Tennessee to Mayo Clinic is to fly which takes 6h 26m and costs $140 - $600. Alternatively, you can bus, which costs $140 - $270 and takes 20h 56m.
Tennessee to Mayo Clinic bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Tennessee to Mayo Clinic is 760 miles. It takes approximately 13h 14m to drive from Tennessee to Mayo Clinic.
What companies run services between Tennessee, USA and Mayo Clinic, MN, USA?
American Airlines, Delta, and United Airlines fly from Mcghee Tyson Airport (TYS) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Central 4Th Ave - Bay 13 to Mayo Clinic via Fulton Station Outbound, Nashville Bus Station, Chicago Bus Station, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, Madison, and Rochester in around 20h 56m.
- Website
- delta.com
Flights from Mcghee Tyson Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $95–500
Flights from Mcghee Tyson Airport to Rochester via Atlanta, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 8h 2m
- When
- Every day
- Estimated price
- $120–600
Flights from Mcghee Tyson Airport to Rochester via Detroit, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 9h 12m
- When
- Every day
- Estimated price
- $110–550
Flights from Mcghee Tyson Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 31m
- When
- Every day
- Estimated price
- $110–600
Flights from Mcghee Tyson Airport to Minneapolis–Saint Paul International Airport via Atlanta
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $140–700
Flights from Nashville to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $95–500
Flights from Memphis to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 8h 24m
- When
- Every day
- Estimated price
- $100–550
Flights from Memphis to Rochester via Detroit, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 9h 42m
- When
- Every day
- Estimated price
- $130–650
Flights from Nashville to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $110–600
Flights from Memphis to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- $110–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Carbondale to Chicago Union Station
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $80–180
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–50
- Website
- Amtrak
Train from Carbondale to Chicago Union Station
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $80–180
- Website
- Amtrak
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $100–240
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Nashville Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 3h 55m
- Frequency
- 5 times a week
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from Nashville Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 3h 55m
- Frequency
- 5 times a week
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from Nashville Bus Station to Chicago Bus Station
- Ave. Duration
- 11h 25m
- Frequency
- Twice daily
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 79+ hotels available in Mayo Clinic.




