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How to get fromTennessee to Mayo Clinicby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Amtrak, Greyhound)

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There are 11 ways to get from Tennessee to Mayo Clinic by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Rochester

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Rochester (RST)plane plane TYS - RST
    6h 53m
    $181–688

  2. Fly Nashville to Rochester

    cheapest
    1. Fly from Nashville (BNA) to Rochester (RST)plane plane BNA - RST
    7h 24m
    $101–473

  3. Bus via Chicago

    1. Take the bus from Nashville Bus Station to Chicago Bus Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    20h 16m
    $152–282

  4. Bus, train

    1. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochester, MNbus bus
    22h 32m
    $290–577

  5. Drive 755.8 mi

    1. Drive from Nashville to Mayo Cliniccar car 755.8 mi
    13h 14m
    $138–200

  6. Fly Mcghee Tyson Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP)plane plane TYS - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 40m
    $249–819

  7. Fly Memphis to Rochester

    1. Fly from Memphis (MEM) to Rochester (RST)plane plane MEM - RST
    6h 54m
    $115–572

  8. Fly Nashville to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Nashville (BNA) to Minneapolis–Saint Paul International Airport (MSP)plane plane BNA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 32m
    $454–1,004

  9. Fly Memphis to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Memphis (MEM) to Minneapolis–Saint Paul International Airport (MSP)plane plane MEM - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 37m
    $173–703

  10. Bus

    1. Take the bus from Nashville to Chicago Union Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    20h 27m
    $152–282

  11. Bus, train via Milwaukee

    1. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Rochesterbus bus
    20h 40m
    $229–427

Tennessee to Mayo Clinic by bus, train, and foot

Calendar12Weekly Services
Duration22h 32mAverage Duration
Ticket$290Cheapest Price
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Questions & Answers

Map of how to get from Tennessee to Mayo Clinic.ExpandLaunch map view
  • Distance: 739.8 mi
  • Duration: 6h 53m

What companies run services between Tennessee, USA and Mayo Clinic, MN, USA?

Delta and American Airlines fly from Mcghee Tyson Airport (TYS) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Central 4Th Ave - Bay 13 to Mayo Clinic via Fulton Station Outbound, Nashville Bus Station, Chicago Bus Station, W Jackson Blvd, after S Clinton St, Madison, and Rochester in around 20h 16m.

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