Rome2Rio

How to get fromTennessee to Mayo Clinicby plane, bus, train, car, bus (Greyhound, Flixbus), or bus (Amtrak)

Find Transport to Mayo Clinic

See all options

There are 11 ways to get from Tennessee to Mayo Clinic by plane, bus, train, car, bus (Greyhound, Flixbus), or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Rochester

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Rochester (RST)plane plane TYS - RST
    6h 10m
    $148–607

  2. Fly Nashville to Rochester

    cheapest
    1. Fly from Nashville (BNA) to Rochester (RST)plane plane BNA - RST
    7h 10m
    $88–512

  3. Bus, train via Milwaukee

    1. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Rochesterbus bus
    20h 45m
    $317–497

  4. Bus, train

    1. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    22h 32m
    $450–712

  5. Drive  755.8 mi

    1. Drive from Nashville to Mayo Cliniccar car 755.8 mi
    13h 14m
    $138–200

  6. Fly Memphis to Rochester

    1. Fly from Memphis (MEM) to Rochester (RST)plane plane MEM - RST
    7h
    $92–531

  7. Fly Mcghee Tyson Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP)plane plane TYS - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 57m
    $227–767

  8. Fly Nashville to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Nashville (BNA) to Minneapolis–Saint Paul International Airport (MSP)plane plane BNA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 52m
    $152–652

  9. Fly Memphis to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Memphis (MEM) to Minneapolis–Saint Paul International Airport (MSP)plane plane MEM - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 52m
    $151–651

  10. Bus

    1. Take the bus from Nashville Bus Station to Chicago Bus Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    20h 56m
    $147–262

  11. Bus via Lafayette

    1. Take the bus from Nashville to Lafayette Amtrak Stationbus bus
    2. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    21h 29m
    $151–247

Tennessee to Mayo Clinic by bus, train, and foot

Calendar5Weekly Services
Duration20h 45mAverage Duration
Ticket$317Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Tennessee to Mayo Clinic.ExpandLaunch map view
  • Distance: 739.8 mi
  • Duration: 6h 10m

What companies run services between Tennessee, USA and Mayo Clinic, MN, USA?

Delta and American Airlines fly from Mcghee Tyson Airport (TYS) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Central 4Th Ave - Bay 13 to Mayo Clinic via Fulton Station Outbound, Nashville Bus Station, Chicago Bus Station, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, Madison, and Rochester in around 20h 56m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There