There are 4 ways to get from Toledo to Santa Ana by train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Torrijos to Cacerestrain Alv / ...
- Take the bus from Cáceres to Santa Anabus
5h 43m€38–59Bus via Trujillo
cheapest- Take the bus from Toledo to Talavera de la Reinabus
- Take the bus from Talavera de La Reina to Trujillobus
6h 8m€26–39Drive 240 km
- Drive from Toledo to Santa Anacar 240 km
2h 35m€38–55Bus
- Take the bus from Toledo to Talavera de la Reinabus
- Take the bus from Talavera de la Reina to Trujillobus Auto Res
6h 20m€28–41
Questions & Answers
The cheapest way to get from Toledo to Santa Ana is to bus via Trujillo which costs €25 - €40 and takes 6h 8m.
The fastest way to get from Toledo to Santa Ana is to drive which takes 2h 35m and costs €35 - €55.
No, there is no direct bus from Toledo to Santa Ana. However, there are services departing from Toledo and arriving at Santa Ana via Talavera de La Reina and Trujillo. The journey, including transfers, takes approximately 6h 8m.
The distance between Toledo and Santa Ana is 324 km. The road distance is 240 km.
The best way to get from Toledo to Santa Ana without a car is to train and bus which takes 5h 43m and costs €35 - €60.
It takes approximately 5h 43m to get from Toledo to Santa Ana, including transfers.
Toledo to Santa Ana bus services, operated by MonBus, depart from Toledo station.
Toledo to Santa Ana bus services, operated by MonBus, arrive at Talavera de la Reina station.
Yes, the driving distance between Toledo to Santa Ana is 240 km. It takes approximately 2h 35m to drive from Toledo to Santa Ana.
There are 84+ hotels available in Santa Ana.
What companies run services between Toledo, Spain and Santa Ana, Extremadura, Spain?
You can take a bus from Toledo to Santa Ana via Talavera de la Reina, Talavera de La Reina, Trujillo, and Trujillo in around 6h 8m.
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Torrijos to Caceres
- Ave. Duration
- 2h 18m
- Frequency
- Hourly
- Estimated price
- €30–50
- Website
- Renfe Viajeros
- Phone
- +34 (0) 927 38 01 27
- [email protected]
- Website
- solistour.com
Bus from Cáceres to Santa Ana
- Ave. Duration
- 52 min
- Frequency
- Twice daily
- Estimated price
- €5
- Schedules at
- solistour.com
- Phone
- +34 900 92 91 92
- [email protected]
- Website
- Monbus
Bus from Toledo to Talavera de la Reina
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- €6–10
- Website
- Monbus
Bus from Toledo to Talavera de la Reina
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- €6–10
- Website
- Monbus
- Phone
- +34 91 272 28 32
- [email protected]
- Website
- avanzabus.com
Bus from Talavera de La Reina to Trujillo
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- €16–26
- Schedules at
- avanzabus.com
Bus from Talavera de la Reina to Trujillo
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €18–28
- Schedules at
- avanzabus.com
Want to know more about travelling around Spain
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Train travel in Spain: A guide to Renfe
Read the travel guide
What are the different types of Renfe trains in Spain?
Read the travel guide

















