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How to get fromToledo to Depewby train (Amtrak), bus, car, plane, or bus (Greyhound)

Find Transport to Depew

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There are 5 ways to get from Toledo to Depew by train (Amtrak), bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Toledo to Buffalo Depew Stationtrain train Lake Shore Limited
    6h 25m
    $74–173
  2. Bus

    cheapest
    1. Take the bus from Toledo to Clevelandbus bus Chicago / ...
    2. Take the bus from Cleveland, OH to Buffalo, NYbus bus Cinncinati,OH-Buffalo / ...
    7h 53m
    $31–107
  3. Drive  305.6 mi

    1. Drive from Toledo to Depewcar car 305.6 mi
    5h 25m
    $56–81
  4. Bus, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Buffalo Niagara International Airport (BUF)plane plane DTW - BUF
    4h 30m
    $115–646
  5. Bus via Brook Park (Greyhound)

    1. Take the bus from Toledo Bus Stop to Cleveland Bus Stationbus bus Greyhound US0420 / ...
    2. Take the bus from Cleveland Bus Station to Buffalobus bus Greyhound US0171 / ...
    8h 13m
    $48–77

Toledo to Depew by train and bus (Amtrak)

Calendar5Weekly Services
Duration6h 25mAverage Duration
Ticket$74Cheapest Price
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Comparing Your Travel Options

What companies run services between Toledo, OH, USA and Depew, NY, USA?

Amtrak operates a train from Toledo to Buffalo Depew Station twice daily. Tickets cost $70–180 and the journey takes 5h 22m. Alternatively, you can take a bus from Toledo to Broadway & Elwood Avenue via Cleveland, OH and Ellicott Street & MTC Static in around 7h 53m.

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Need to know: Greyhound

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