Rome2Rio

How to get fromToledo to Des Moinesby bus, plane, train, bus (Amtrak, Greyhound), car, or bus (Greyhound, Flixbus)

Find Transport to Des Moines

See all options

There are 9 ways to get from Toledo to Des Moines by bus, plane, train, bus (Amtrak, Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Detroit, fly

    best
    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    5h 19m

  2. Bus

    cheapest
    1. Take the bus from Toledo Bus Stop to Chicago Bus Stationbus bus Greyhound US0164
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0155S / ...
    14h 50m
    $89–163

  3. Train, bus via Galesburg

    1. Take the train from Toledo to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    3. Take the bus from Galesburg to Des Moinesbus bus
    13h 54m
    $249–398

  4. Bus via Chicago

    1. Take the bus from Toledo to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0155S / ...
    13h 56m

  5. Drive  555.8 mi

    1. Drive from Toledo to Des Moinescar car 555.8 mi
    9h 19m
    $99–142

  6. Bus to Cleveland-Hopkins International Airport, fly

    1. Take the bus from Toledo Bus Stop to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM)plane plane CLE - DSM
    7h 6m
    $125–544

  7. Bus to Fort Wayne International Airport, fly

    1. Take the bus from Toledo Bus Stop to Ft Wayne Citilink Central Stationbus bus
    2. Fly from Fort Wayne International Airport (FWA) to Des Moines (DSM)plane plane FWA - DSM
    7h 25m
    $108–446

  8. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Toledo to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane plane ORD - DSM
    8h 3m
    $192–489

  9. Train, bus

    1. Take the train from Toledo to Chicago Union Stationtrain train Floridian / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0155S / ...
    13h 57m
    $194–298

Toledo to Des Moines by train and bus

Calendar14Weekly Services
Duration13h 54mAverage Duration
Ticket$249Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Toledo to Des Moines.ExpandLaunch map view
  • Distance: 620.8 mi
  • Duration: 5h 19m

What companies run services between Toledo, OH, USA and Des Moines, IA, USA?

You can take a bus from Toledo to Des Moines via Chicago Union Station and Chicago Bus Station in around 13h 56m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There