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How to get fromToledo to La Crosseby train (Amtrak), bus (Amtrak, Greyhound, Flixbus), car, bus, plane, bus (Greyhound, Flixbus), or train

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There are 8 ways to get from Toledo to La Crosse by train (Amtrak), bus (Amtrak, Greyhound, Flixbus), car, bus, plane, bus (Greyhound, Flixbus), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Toledo to Chicago Union Stationtrain train Floridian / ...
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    10h 22m
    $279–437

  2. Bus

    cheapest
    1. Take the bus from Toledo Bus Stop to Chicago Bus Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to La Crossebus bus
    13h 10m
    $84–173

  3. Bus via Milwaukee

    1. Take the bus from Toledo to Chicago Union Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to La Crossebus bus
    11h 46m

  4. Drive  521.5 mi

    1. Drive from Toledo to La Crossecar car 521.5 mi
    8h 45m
    $90–129

  5. Bus to Detroit, fly to La Crosse

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to La Crosse (LSE)plane plane DTW - LSE
    7h 37m

  6. Train to Chicago O'Hare International Airport, fly to La Crosse

    1. Take the train from Toledo to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to La Crosse (LSE)plane plane ORD - LSE
    7h 58m
    $188–478

  7. Bus to Detroit, fly to Dane County Regional Airport-Truax Field, bus

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Dane County Regional Airport-Truax Field (MSN)plane plane DTW - MSN
    3. Take the bus from Madison to La Crossebus bus
    8h 48m

  8. Bus to Detroit, fly to Minneapolis–Saint Paul International Airport, train

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Minneapolis–Saint Paul International Airport (MSP)plane plane DTW - MSP
    3. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    9h 29m

Toledo to La Crosse by train (Amtrak)

Calendar21Weekly Trains
Duration10h 22mAverage Duration
Ticket$279Cheapest Price
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Comparing Your Travel Options

Map of how to get from Toledo to La Crosse.ExpandLaunch map view
  • Distance: 512.5 mi
  • Duration: 10h 22m

What companies run services between Toledo, OH, USA and La Crosse, WI, USA?

You can take a train from Toledo to La Crosse Amtrak Station via Chicago Union Station in around 10h 22m. Alternatively, you can take a bus from Toledo to La Crosse via Chicago Union Station, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 11h 46m.

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