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How to get fromToledo to Sikestonby bus, taxi, train, car, plane, or bus (Amtrak)

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There are 11 ways to get from Toledo to Sikeston by bus, taxi, train, car, plane, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Toledo Bus Stop to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    4. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    12h 55m
    $190–279

  2. Drive  546.4 mi

    cheapest
    1. Drive from Toledo to Sikestoncar car 546.4 mi
    9h 16m
    $94–135

  3. Train, drive (Amtrak)

    1. Take the train from Toledo to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fulton Amtrak Stationtrain train
    3. Drive from Fulton Amtrak Station to Sikestoncar car
    14h 39m
    $359–563

  4. Bus to Detroit, fly to Barkley Regional Airport, drive

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Barkley Regional Airport (PAH)plane plane DTW - PAH
    3. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    8h 42m

  5. Train, bus

    1. Take the train from Toledo to Chicago Union Stationtrain train Floridian / ...
    2. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    13h 47m
    $242–344

  6. Bus

    1. Take the bus from Toledo to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    2. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    14h 26m

  7. Bus to Detroit, fly to Lambert–St. Louis International Airport, bus, taxi

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    4. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    9h 10m

  8. Train to Cleveland-Hopkins International Airport, fly to Lambert–St. Louis International Airport, bus, taxi

    1. Take the train from Toledo to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    4. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    10h 1m
    $285–901

  9. Bus to Detroit, fly to Nashville, bus, drive

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Nashville (BNA)plane plane DTW - BNA
    3. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    4. Drive from Paducah Bus Station to Sikestoncar car
    10h 18m

  10. Bus to Detroit, fly to Cape Girardeau Municipal Airport, taxi

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Cape Girardeau Municipal Airport (CGI)plane plane DTW - CGI
    3. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    9h 24m

  11. Bus to Detroit, fly to Memphis, bus

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Memphis (MEM)plane plane DTW - MEM
    3. Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus bus
    10h 27m

Detroit (DTW) to Barkley Regional Airport (PAH) flights

Calendar26Weekly Planes
Duration6h 52mAverage Duration
Ticket$96Cheapest Price
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Comparing Your Travel Options

Map of how to get from Toledo to Sikeston.ExpandLaunch map view
  • Distance: 608.6 mi
  • Duration: 12h 55m

What companies run services between Toledo, OH, USA and Sikeston, MO, USA?

You can take a bus from Toledo to Sikeston via Chicago Union Station, Clinton & Jackson, Cicero & 24th Place Terminal, Tornado Bus Co - Chicago, and Flying J - Matthews in around 14h 26m.

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