There are 6 ways to get from Topeka to Cape Girardeau by bus (Greyhound), train, bus, car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Topeka to St Louis Bus Stationbus Greyhound US1200 / ...
- Take the bus from St Louis Bus Station to Cape Girardeaubus Greyhound US1173
9h 24m$75–137Train, bus
- Take the train from Topeka Station to Kansas Citytrain
- Take the train from Kansas City to St. Louistrain
- Take the bus from St Louis Bus Station to Cape Girardeaubus
11h 50m$137–277Drive 408.5 mi
- Drive from Topeka to Cape Girardeaucar 408.5 mi
6h 52m$75–108Bus to Kansas City, fly to Williamson County Regional Airport, taxi
- Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus
- Fly from Kansas City (MCI) to Williamson County Regional Airport (MWA)plane MCI - MWA
- Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi
9h 44m$283–814Drive to Manhattan Regional Airport, fly to Cape Girardeau Municipal Airport
- Drive from Topeka to Manhattan Regional Airport (MHK)car
- Fly from Manhattan Regional Airport (MHK) to Cape Girardeau Municipal Airport (CGI)plane MHK - CGI
7h 2m$120–455Bus to Kansas City, fly to Lambert–St. Louis International Airport, bus
- Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus
- Fly from Kansas City (MCI) to Lambert–St. Louis International Airport (STL)plane MCI - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
8h 52m$156–701
Kansas City (MCI) to Williamson County Regional Airport (MWA) flights
Questions & Answers
The cheapest way to get from Topeka to Cape Girardeau is to bus which costs $75 - $140 and takes 9h 24m.
The fastest way to get from Topeka to Cape Girardeau is to drive which takes 6h 52m and costs $70 - $110.
No, there is no direct bus from Topeka to Cape Girardeau. However, there are services departing from Topeka and arriving at Cape Girardeau via St Louis Bus Station. The journey, including transfers, takes approximately 9h 24m.
The distance between Topeka and Cape Girardeau is 429 miles. The road distance is 410.9 miles.
The best way to get from Topeka to Cape Girardeau without a car is to bus which takes 9h 24m and costs $75 - $140.
It takes approximately 9h 24m to get from Topeka to Cape Girardeau, including transfers.
Topeka to Cape Girardeau bus services, operated by Greyhound USA, depart from Topeka station.
Topeka to Cape Girardeau bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Yes, the driving distance between Topeka to Cape Girardeau is 411 miles. It takes approximately 6h 52m to drive from Topeka to Cape Girardeau.
Book your Topeka to Cape Girardeau bus tickets online with Omio.
What companies run services between Topeka, KS, USA and Cape Girardeau, MO, USA?
You can take a bus from Topeka to Cape Girardeau via St Louis Bus Station and Cape Girardeau in around 9h 24m.
- Website
- southwest.com
Flights from Kansas City to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $85–600
- Website
- contouraviation.com
Flights from Kansas City to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $110–600
Flights from Manhattan Regional Airport to Cape Girardeau Municipal Airport via Chicago O'Hare
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $85–410
Flights from Manhattan Regional Airport to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 48m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $220–900
- Website
- aa.com
Flights from Kansas City to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Topeka Station to Kansas City
- Ave. Duration
- 2h 1m
- Frequency
- Once daily
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Topeka to St Louis Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Twice daily
- Estimated price
- $50–95
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
- Phone
- +1 800-923-1799
- [email protected]
- Website
- omnibusexpress.com
Bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas City
- Ave. Duration
- 51 min
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- omnibusexpress.com
Bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas City
- Ave. Duration
- 51 min
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- omnibusexpress.com
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More Questions & Answers
There are 16+ hotels available in Cape Girardeau.










