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How to get fromTopeka to La Crosseby bus (Greyhound, Flixbus), train (Amtrak), car, plane, or bus

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There are 6 ways to get from Topeka to La Crosse by bus (Greyhound, Flixbus), train (Amtrak), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Topeka to Kansas City Bus Stationbus bus
    2. Take the bus from Kansas City to St. Paulbus bus
    3. Take the bus from St. Paul to La Crossebus bus
    14h 55m
    $149–230

  2. Drive  492.5 mi

    cheapest
    1. Drive from Topeka to La Crossecar car 492.5 mi
    9h 10m
    $90–130

  3. Train (Amtrak)

    1. Take the train from Topeka Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    16h 16m
    $189–462

  4. Drive to Manhattan Regional Airport, fly

    1. Drive from Topeka to Manhattan Regional Airport (MHK)car car
    2. Fly from Manhattan Regional Airport (MHK) to La Crosse (LSE)plane plane MHK - LSE
    12h
    $101–440

  5. Bus via Des Moines

    1. Take the bus from Topeka to Kansas City Bus Stationbus bus
    2. Take the bus from Kansas City Bus Station to Des Moinesbus bus
    3. Take the bus from Des Moines to Minneapolis Bus Stationbus bus
    4. Take the bus from Minneapolis to La Crossebus bus
    15h 55m
    $119–190

  6. Bus to Kansas City, fly

    1. Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus bus
    2. Fly from Kansas City (MCI) to La Crosse (LSE)plane plane MCI - LSE
    8h 56m
    $152–627

Topeka to La Crosse by bus

Calendar7Weekly Buses
Duration14h 55mAverage Duration
Ticket$149Cheapest Price
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Comparing Your Travel Options

Map of how to get from Topeka to La Crosse.ExpandLaunch map view
  • Distance: 660.5 mi
  • Duration: 14h 55m

What companies run services between Topeka, KS, USA and La Crosse, WI, USA?

You can take a bus from Topeka to La Crosse via Kansas City Bus Station, Kansas City, and St. Paul in around 14h 55m. Alternatively, you can take a train from Topeka Station to La Crosse Amtrak Station via Chicago Union Station in around 16h 16m.

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