Rome2Rio

How to get fromTopeka to La Crosseby car, plane, bus (Greyhound, Flixbus), train (Amtrak), or bus

Find Transport to La Crosse

See all options

There are 6 ways to get from Topeka to La Crosse by car, plane, bus (Greyhound, Flixbus), train (Amtrak), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Manhattan Regional Airport, fly

    best
    1. Drive from Topeka to Manhattan Regional Airport (MHK)car car
    2. Fly from Manhattan Regional Airport (MHK) to La Crosse (LSE)plane plane MHK - LSE
    5h 34m
    $106–440

  2. Drive 492.5 mi

    cheapest
    1. Drive from Topeka to La Crossecar car 492.5 mi
    9h 10m
    $90–130

  3. Bus

    1. Take the bus from Topeka to Kansas City Bus Stationbus bus
    2. Take the bus from Kansas City to St. Paulbus bus
    3. Take the bus from St. Paul to La Crossebus bus
    14h 55m
    $114–212

  4. Train (Amtrak)

    1. Take the train from Topeka Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    16h 16m
    $228–496

  5. Bus to Kansas City, fly

    1. Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus bus
    2. Fly from Kansas City (MCI) to La Crosse (LSE)plane plane MCI - LSE
    8h 58m
    $157–627

  6. Bus via Des Moines

    1. Take the bus from Topeka to Kansas City Bus Stationbus bus
    2. Take the bus from Kansas City Bus Station to Des Moinesbus bus
    3. Take the bus from Des Moines to Saint Paul Union Depotbus bus
    4. Take the bus from St. Paul to La Crossebus bus
    16h 16m
    $112–207

Topeka to La Crosse by bus

Calendar7Weekly Buses
Duration14h 55mAverage Duration
Ticket$114Cheapest Price
See schedules

Questions & Answers

Map of how to get from Topeka to La Crosse.ExpandLaunch map view
  • Distance: 501.1 mi
  • Duration: 5h 34m

What companies run services between Topeka, KS, USA and La Crosse, WI, USA?

You can take a bus from Topeka to La Crosse via Kansas City Bus Station, Kansas City, and St. Paul in around 14h 55m. Alternatively, you can take a train from Topeka Station to La Crosse Amtrak Station via Chicago Union Station in around 16h 16m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers