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How to get fromTopeka to Mayo Clinicby bus (Greyhound, Flixbus), car, bus, or plane

Find Transport to Mayo Clinic

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There are 5 ways to get from Topeka to Mayo Clinic by bus (Greyhound, Flixbus), car, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Topeka to Kansas City Bus Stationbus bus
    2. Take the bus from Kansas City to Owatonnabus bus
    3. Take the bus from Owatonna to Rochesterbus bus
    11h 18m
    $105–186

  2. Drive  461.1 mi

    cheapest
    1. Drive from Topeka to Mayo Cliniccar car 461.1 mi
    7h 37m
    $85–122

  3. Bus to Kansas City, fly to Rochester

    1. Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus bus
    2. Fly from Kansas City (MCI) to Rochester (RST)plane plane MCI - RST
    8h 52m
    $124–564

  4. Bus to Kansas City, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus bus
    2. Fly from Kansas City (MCI) to Minneapolis–Saint Paul International Airport (MSP)plane plane MCI - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 20m
    $595–1,056

  5. Bus to Wichita Mid-Continent Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Quincy Street Station - Topeka to 2210 Somerset St - Wichitabus bus
    2. Fly from Wichita Mid-Continent Airport (ICT) to Minneapolis–Saint Paul International Airport (MSP)plane plane ICT - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 11m
    $250–849

Topeka to Mayo Clinic by bus and foot

Calendar14Weekly Services
Duration11h 18mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

Map of how to get from Topeka to Mayo Clinic.ExpandLaunch map view
  • Distance: 484.2 mi
  • Duration: 11h 18m

What companies run services between Topeka, KS, USA and Mayo Clinic, MN, USA?

You can take a bus from Topeka to Mayo Clinic via Kansas City Bus Station, Kansas City, Owatonna, and Rochester in around 11h 18m.

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Bus operators

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