There are 6 ways to get from Topeka to Mayo Clinic by bus (Greyhound, Flixbus), car, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Topeka to Kansas City Bus Stationbus
- Take the bus from Kansas City to St. Paulbus
- Take the bus from St. Paul to Rochesterbus
13h 8m$138–206Drive 461.1 mi
cheapest- Drive from Topeka to Mayo Cliniccar 461.1 mi
7h 37m$85–122Bus to Kansas City, fly to Rochester
- Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus
- Fly from Kansas City (MCI) to Rochester (RST)plane MCI - RST
9h 36m$124–584Bus via Des Moines
- Take the bus from Topeka to Kansas City Bus Stationbus
- Take the bus from Kansas City Bus Station to Des Moinesbus
- Take the bus from Des Moines to Minneapolis Bus Stationbus
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
14h 36m$132–188Bus to Kansas City, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas Citybus
- Fly from Kansas City (MCI) to Minneapolis–Saint Paul International Airport (MSP)plane MCI - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
8h 40m$533–1,104Bus to Wichita Mid-Continent Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Quincy Street Station - Topeka to 2210 Somerset St - Wichitabus
- Fly from Wichita Mid-Continent Airport (ICT) to Minneapolis–Saint Paul International Airport (MSP)plane ICT - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
9h 32m$238–847
Topeka to Mayo Clinic by bus and foot
Comparing Your Travel Options
The cheapest way to get from Topeka to Mayo Clinic is to drive which costs $80 - $130 and takes 7h 37m.
The fastest way to get from Topeka to Mayo Clinic is to drive which takes 7h 37m and costs $80 - $130.
No, there is no direct bus from Topeka to Mayo Clinic. However, there are services departing from Topeka and arriving at Rochester via Kansas City and St. Paul. The journey, including transfers, takes approximately 13h 8m.
The distance between Topeka and Mayo Clinic is 589 miles. The road distance is 463.8 miles.
The best way to get from Topeka to Mayo Clinic without a car is to bus which takes 13h 8m and costs $130 - $210.
It takes approximately 13h 8m to get from Topeka to Mayo Clinic, including transfers.
Topeka to Mayo Clinic bus services, operated by Greyhound USA, depart from Topeka station.
Topeka to Mayo Clinic bus services, operated by Greyhound USA, arrive at Kansas City Bus Station.
Yes, the driving distance between Topeka to Mayo Clinic is 464 miles. It takes approximately 7h 37m to drive from Topeka to Mayo Clinic.
There are 78+ hotels available in Mayo Clinic.
What companies run services between Topeka, KS, USA and Mayo Clinic, MN, USA?
You can take a bus from Topeka to Mayo Clinic via Kansas City Bus Station, Kansas City, St. Paul, and Rochester in around 13h 8m.
- Website
- delta.com
Flights from Kansas City to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $80–490
Flights from Kansas City to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $90–600
Flights from Wichita Mid-Continent Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $110–700
- Website
- southwest.com
Flights from Kansas City to Minneapolis–Saint Paul International Airport via St. Louis
- Ave. Duration
- 3h 20m
- When
- Saturday
- Estimated price
- $120–700
Flights from Kansas City to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 3h 48m
- When
- Monday to Wednesday
- Estimated price
- $130–700
Flights from Wichita Mid-Continent Airport to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 4h 15m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $160–800
- Website
- aa.com
Flights from Kansas City to Rochester via Chicago O'Hare
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $95–550
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Topeka to Kansas City Bus Station
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Estimated price
- $11–17
- Website
- Greyhound
Bus from Topeka to Kansas City Bus Station
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Estimated price
- $11–17
- Website
- Greyhound
Bus from Kansas City Bus Station to Des Moines
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- Greyhound
Bus from Des Moines to Minneapolis Bus Station
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Topeka to Kansas City Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 6 times a week
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
Bus from Topeka to Kansas City Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 6 times a week
- Estimated price
- $9–15
- Schedules at
- Flixbus USA
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to St. Paul
- Ave. Duration
- 8h 25m
- Frequency
- Twice daily
- Estimated price
- $100–150
- Book at
- Jefferson Lines
- Adult
- $100–150
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas City
- Ave. Duration
- 51 min
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- Omnibus Express
Bus from Quincy Street Station - Topeka to 2745 Southwest Blvd - Kansas City
- Ave. Duration
- 51 min
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- Omnibus Express
Bus from Quincy Street Station - Topeka to 2210 Somerset St - Wichita
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $50–65
- Schedules at
- Omnibus Express
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
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