There are 10 ways to get from Toulouse to Siena by train (TGV, Trenitalia), bus, car, plane, train, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Toulouse Matabiau to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
14h 51m€203–326Fly Toulouse-Blagnac Airport to Florence Peretola Airport, train
cheapest- Fly from Toulouse-Blagnac Airport (TLS) to Florence Peretola Airport (FLR)plane TLS - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 30m€76–286Bus
- Take the bus from Toulouse to Florence Villa Constanza Bus Stationbus N718
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 1518 / ...
16h 5m€99–145Drive 1,020 km
- Drive from Toulouse to Sienacar 1,020 km
10h 34m€194–280Fly Toulouse-Blagnac Airport to Bologna Guglielmo Marconi Airport, train
- Fly from Toulouse-Blagnac Airport (TLS) to Bologna Guglielmo Marconi Airport (BLQ)plane TLS - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
9h 19m€104–286Train via Marseille
- Take the train from Toulouse Matabiau to Marseille St Charlestrain
- Take the train from Marseille-Saint-Charles to Nice-Villetrain
- Take the train from Ventimiglia to Pisa Centraletrain Ic
- Take the train from Pisa Centrale to Empolitrain Re
- Take the train from Empoli to Sienatrain Re
16h 19m€182–295Fly Toulouse-Blagnac Airport to Pisa International Airport, train
- Fly from Toulouse-Blagnac Airport (TLS) to Pisa International Airport (PSA)plane TLS - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
6h 23m€80–314Fly Toulouse-Blagnac Airport to Fiumicino International Airport, train
- Fly from Toulouse-Blagnac Airport (TLS) to Fiumicino International Airport (FCO)plane TLS - FCO
- Take the train from Roma Termini to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
9h 8m€100–280Fly Toulouse-Blagnac Airport to Nice Côte D'Azur International Airport, train
- Fly from Toulouse-Blagnac Airport (TLS) to Nice Côte D'Azur International Airport (NCE)plane TLS - NCE
- Take the train from Saint-Laurent-du-Var to Ventimigliatrain
- Take the train from Ventimiglia to Genova P.Za Principetrain
- Take the train from Genova P.Za Principe to Pisa Centraletrain
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
11h 53m€127–310Train, train to Barcelona–El Prat Airport, fly to Florence Peretola Airport
- Take the train from Toulouse Matabiau to Narbonnetrain
- Take the train from Narbonne to Barcelona-Santstrain
- Fly from Barcelona–El Prat Airport (BCN) to Florence Peretola Airport (FLR)plane BCN - FLR
- Take the train from Firenze S.M.N. to Sienatrain
11h 43m€111–291
Toulouse to Siena by train
Comparing Your Travel Options
The cheapest way to get from Toulouse to Siena is to bus which costs €95 - €150 and takes 16h 5m.
The fastest way to get from Toulouse to Siena is to fly and train which takes 6h 23m and costs €80 - €320.
No, there is no direct bus from Toulouse to Siena. However, there are services departing from Toulouse and arriving at Siena via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 16h 5m.
No, there is no direct train from Toulouse to Siena. However, there are services departing from Toulouse Matabiau and arriving at Siena via Lyon Part Dieu, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 14h 51m.
The distance between Toulouse and Siena is 1396 km. The road distance is 1020 km.
The best way to get from Toulouse to Siena without a car is to train which takes 14h 51m and costs €200 - €330.
It takes approximately 14h 51m to get from Toulouse to Siena, including transfers.
Toulouse to Siena bus services, operated by FlixBus, depart from Toulouse station.
Toulouse to Siena train services, operated by TGV inOui, depart from Toulouse Matabiau station.
The best way to get from Toulouse to Siena is to train which takes 14h 51m and costs €200 - €330. Alternatively, you can bus, which costs €95 - €150 and takes 16h 5m.
What companies run services between Toulouse, France and Siena, Italy?
You can take a train from Toulouse Matabiau to Siena via Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 14h 51m. Alternatively, you can take a bus from Toulouse to Siena via Florence Villa Constanza Bus Station in around 16h 5m.
- Website
- easyjet.com
Flights from Toulouse-Blagnac Airport to Fiumicino International Airport via Lyon
- Ave. Duration
- 3h 45m
- When
- Monday to Friday
- Estimated price
- €85–210
Flights from Toulouse-Blagnac Airport to Nice Côte D'Azur International Airport
- Ave. Duration
- 1h 8m
- When
- Thursday, Friday, Wednesday, Monday, and Sunday
- Estimated price
- €50–180
- Website
- volotea.com
Flights from Toulouse-Blagnac Airport to Bologna Guglielmo Marconi Airport via Fiumicino International Airport
- Ave. Duration
- 4h 20m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €70–220
Flights from Toulouse-Blagnac Airport to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Monday and Friday
- Estimated price
- €35–260
Flights from Toulouse-Blagnac Airport to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Sunday
- Estimated price
- €30–150
Flights from Barcelona–El Prat Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- €85–190
- Website
- vueling.com
Flights from Barcelona–El Prat Airport to Florence Peretola Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- €40–130
- Website
- lufthansa.com
Flights from Toulouse-Blagnac Airport to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- €95–200
- Website
- ita-airways.com
Flights from Toulouse-Blagnac Airport to Bologna Guglielmo Marconi Airport via Fiumicino International Airport
- Ave. Duration
- 4h 20m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €70–220
Flights from Barcelona–El Prat Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- €85–190
- Website
- ryanair.com
Flights from Toulouse-Blagnac Airport to Bologna Guglielmo Marconi Airport via Palma Mallorca
- Ave. Duration
- 5h 40m
- When
- Sunday
- Estimated price
- €70–220
Flights from Toulouse-Blagnac Airport to Fiumicino International Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €45–170
- Website
- airfrance.com
Flights from Toulouse-Blagnac Airport to Nice Côte D'Azur International Airport via Lyon
- Ave. Duration
- 2h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €45–280
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Toulouse Matabiau to Lyon Part Dieu
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- €110–170
- Website
- TGV inOui
Train from Toulouse Matabiau to Narbonne
- Ave. Duration
- 1h 14m
- Frequency
- 3 times a day
- Estimated price
- €30–45
- Website
- TGV inOui
Train from Narbonne to Barcelona-Sants
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- €50–75
- Website
- TGV inOui
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- 5 times a day
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Ventimiglia to Genova P.Za Principe
- Ave. Duration
- 2h 20m
- Frequency
- Every 3 hours
- Estimated price
- €17–23
- Website
- Trenitalia
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 3h 32m
- Frequency
- Once a week
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Every 2 hours
- Estimated price
- €40–70
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 42m
- Frequency
- Hourly
- Estimated price
- €35–60
- Website
- Trenitalia Frecce
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 1h 57m
- Frequency
- Every 4 hours
- Estimated price
- €22–40
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- 4 times a day
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 41 min
- Frequency
- 5 times a day
- Estimated price
- €10–18
- Website
- Italo Treno
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- 4 times a day
- Estimated price
- €30–50
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €10–18
- Website
- Trenitalia Intercity
Train from Ventimiglia to Pisa Centrale
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
Train from Ventimiglia to Genova P.Za Principe
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- €15–28
- Website
- Trenitalia Intercity
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 2h 14m
- Frequency
- Every 4 hours
- Estimated price
- €17–35
- Website
- Trenitalia Intercity
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Toulouse Matabiau to Marseille St Charles
- Ave. Duration
- 3h 54m
- Frequency
- Every 4 hours
- Estimated price
- €75–130
- Website
- Oui.SNCF
Train from Toulouse Matabiau to Narbonne
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €27–45
- Website
- Oui.SNCF
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Marseille-Saint-Charles to Nice-Ville
- Ave. Duration
- 2h 41m
- Frequency
- Hourly
- Estimated price
- €55–80
- Website
- Zou! Lignes Express Régionales
Train from Saint-Laurent-du-Var to Ventimiglia
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- Zou! Lignes Express Régionales
- Phone
- +33 4 13 94 30 50
- Website
- ZOU!
Train from Saint-Laurent-du-Var to Ventimiglia
- Ave. Duration
- 1h 6m
- Frequency
- Every 30 minutes
- Schedules at
- ZOU!
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Narbonne to Barcelona-Sants
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- €30–45
- Website
- Renfe Viajeros
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Toulouse to Florence Villa Constanza Bus Station
- Ave. Duration
- 14h 15m
- Frequency
- 5 times a week
- Estimated price
- €90–140
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €6–9
- Website
- Flixbus
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Booking & Getting There
Toulouse to Siena bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Toulouse to Siena train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Yes, the driving distance between Toulouse to Siena is 1020 km. It takes approximately 10h 34m to drive from Toulouse to Siena.
Book your Toulouse to Siena train tickets online with Omio.
Book your Toulouse to Siena bus tickets online with Omio and FlixBus.
There are 2286+ hotels available in Siena.


































