There are 4 ways to get from Trinidad to Cayo Guillermo by bus, taxi, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, taxi
best- Take the bus from Terminal de Ómnibus Nacionales Trinidad to Sancti Spíritusbus
- Take the bus from Sancti Spíritus to Ciego de Avilabus
- Take the taxi from Morón to Cayo Guillermotaxi
6h 52m$75–96Drive 270.1 km
cheapest- Drive from Trinidad to Cayo Guillermocar 270.1 km
3h 56m$31–45Bus, drive
- Take the bus from Trinidad to Santa Clarabus
- Take the bus from Santa Clara to Cayo Santa Maríabus
- Drive from Cayo Santa María to Cayo Guillermocar
11h 14m$37–63Bus, drive via Valentin Perla Blanca
- Take the bus from Trinidad to Santa Clarabus
- Take the bus from Santa Clara to Cayo Santa Maríabus
- Drive from Valentin Perla Blanca to Cayo Guillermocar
12h 8m$38–63
Questions & Answers
The cheapest way to get from Trinidad to Cayo Guillermo is to drive which costs $30 - $45 and takes 3h 56m.
The fastest way to get from Trinidad to Cayo Guillermo is to drive which takes 3h 56m and costs $30 - $45.
The distance between Trinidad and Cayo Guillermo is 280 km. The road distance is 270.1 km.
The best way to get from Trinidad to Cayo Guillermo without a car is to bus and taxi which takes 6h 52m and costs $75 - $100.
It takes approximately 6h 52m to get from Trinidad to Cayo Guillermo, including transfers.
Yes, the driving distance between Trinidad to Cayo Guillermo is 270 km. It takes approximately 3h 56m to drive from Trinidad to Cayo Guillermo.
What companies run services between Trinidad, Cuba and Cayo Guillermo, Cuba?
There is no direct connection from Trinidad to Cayo Guillermo. However, you can take the bus to Sancti Spíritus, take the bus to Independencia, walk to Sancti Spíritus, take the bus to Ciego de Avila, walk to Ciego de Ávila, take the bus to Morón, then take the taxi to Cayo Guillermo. Alternatively, you can drive from Trinidad to Cayo Guillermo in around 3h 56m.
- Phone
- +53 7873 7373
- [email protected]
- Website
- eon.wetransp.com
Bus from Terminal de Ómnibus Nacionales Trinidad to Sancti Spíritus
- Ave. Duration
- 1h 15m
- Frequency
- Twice a week
- Estimated price
- $1
- Schedules at
- eon.wetransp.com
Bus from Trinidad to Santa Clara
- Ave. Duration
- 4h
- Frequency
- 3 times a week
- Estimated price
- $1–2
- Schedules at
- eon.wetransp.com
Bus from Trinidad to Santa Clara
- Ave. Duration
- 4h
- Frequency
- 3 times a week
- Estimated price
- $1–2
- Schedules at
- eon.wetransp.com
- Phone
- +53 59 89 0616
- [email protected]
- Website
- viazul.wetransp.com
Bus from Sancti Spíritus to Ciego de Avila
- Ave. Duration
- 1h 1m
- Frequency
- Twice daily
- Estimated price
- $9–14
- Website
- https://www.viazul.wetransp.com/
Bus from Santa Clara to Cayo Santa María
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- https://www.viazul.wetransp.com/
Bus from Santa Clara to Cayo Santa María
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- https://www.viazul.wetransp.com/
- Ave. Duration
- 1h 19m
- Estimated price
- $65–80
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Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including The beginner’s guide to the 2018 World Nomad Games, Getting around the Cyclades, and Travelling to the US: What do I need to know? - to help you get the most out of your next trip.







