There are 7 ways to get from Tucson to La Mesa by plane, tram, train, bus, bus (Flixbus, Greyhound), car, train (Amtrak), or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Tucson, tram
best- Fly from Tucson (TUS) to San Diego International Airport (SAN)plane TUS - SAN
- Take the tram from Civic Center Station to La Mesa Blvd Stationtram
4h 28m$404–770Drive 399.9 mi
cheapest- Drive from Tucson to La Mesacar 399.9 mi
6h 19m$73–106Train, bus
- Take the train from Tucson Amtrak Station to Yuma Amtraktrain
- Take the bus from 3rd Street @ Gila Street to 7th Street @ State Streetbus 10
- Take the bus from El Centro Bus Stop to El Cajon Transit Centerbus
10h 16m$158–242Bus
- Take the bus from Tucson Downtown to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus FlixBus 2047 / ...
- Take the bus from Phoenix Bus Station to El Cajon Transit Centerbus Greyhound US0851S
12h 9m$78–122Bus to Phoenix, fly
- Take the bus from University of Phoenix to Sky Harbor International Airportbus
- Fly from Phoenix (PHX) to San Diego International Airport (SAN)plane PHX - SAN
5h 39m$129–346Train (Amtrak)
- Take the train from Tucson Amtrak Station to Los Angelestrain Texas Eagle / ...
- Take the train from Los Angeles to San Diego Old Town Transportation Centertrain Pacific Surfliner
14h 33m$344–549Shuttle, bus
- Take a shuttle bus from Tucson to Puerto Peñasco
- Take the bus from Puerto Peñasco to Tijuanabus
17h 31m$156–219
Tucson to La Mesa by train, bus, and tram
Comparing Your Travel Options
The cheapest way to get from Tucson to La Mesa is to drive which costs $70 - $110 and takes 6h 19m.
The fastest way to get from Tucson to La Mesa is to fly and tram which takes 4h 28m and costs $400 - $800.
No, there is no direct bus from Tucson to La Mesa. However, there are services departing from Broadway/Country Club and arriving at El Cajon Transit Center via Tucson Downtown and Phoenix Bus Station. The journey, including transfers, takes approximately 12h 9m.
No, there is no direct train from Tucson station to La Mesa station. However, there are services departing from Tucson Amtrak Station and arriving at 70th Street Station via Los Angeles and Old Town Station. The journey, including transfers, takes approximately 14h 33m.
The distance between Tucson and La Mesa is 397 miles. The road distance is 402.3 miles.
The best way to get from Tucson to La Mesa without a car is to train and bus which takes 10h 16m and costs $150 - $250.
It takes approximately 4h 28m to get from Tucson to La Mesa, including transfers.
Tucson to La Mesa bus services, operated by Flixbus USA, depart from Tucson Downtown station.
Tucson to La Mesa train services, operated by Amtrak, depart from Tucson Amtrak Station.
The best way to get from Tucson to La Mesa is to bus which takes 12h 9m and costs $75 - $130. Alternatively, you can train, which costs $340 - $550 and takes 14h 33m.
What companies run services between Tucson, AZ, USA and La Mesa, CA, USA?
You can take a bus from Broadway/Country Club to La Mesa Blvd Station via Downtown Ronstadt Center, Tucson Downtown, Phoenix Sky Harbor Airport/44th Street Sky Train Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, 24th St Station, Phoenix Bus Station, El Cajon Transit Center, and El Cajon Station in around 12h 9m. Alternatively, you can take a train from Tucson Amtrak Station to 70th Street Station via Los Angeles, San Diego Old Town Transportation Center, and Old Town Station in around 14h 33m.
- Website
- southwest.com
Flights from Tucson to San Diego International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $55–370
Flights from Tucson to San Diego International Airport via Phoenix
- Ave. Duration
- 3h 30m
- When
- Monday, Thursday, and Friday
- Estimated price
- $60–380
Flights from Tucson to San Diego International Airport via Las Vegas
- Ave. Duration
- 3h 32m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $75–420
Flights from Phoenix to San Diego International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $35–250
Flights from Phoenix to San Diego International Airport via Las Vegas
- Ave. Duration
- 3h 17m
- When
- Friday, Monday, Thursday, and Sunday
- Estimated price
- $45–280
- Website
- aa.com
Flights from Tucson to San Diego International Airport via Phoenix
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- $60–380
Flights from Phoenix to San Diego International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $35–250
- Website
- alaskaair.com
Flights from Phoenix to San Diego International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $160–240
- Website
- flyfrontier.com
Flights from Phoenix to San Diego International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $70–240
- Phone
- +1 619-557-4555
- Website
- MTS
Tram from Civic Center Station to La Mesa Blvd Station
- Ave. Duration
- 39 min
- Frequency
- Every 20 minutes
- Estimated price
- $2–15
- Website
- MTS
- Schedules at
- MTS Schedules
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Tucson Amtrak Station to Yuma Amtrak
- Ave. Duration
- 4h 34m
- Frequency
- 6 times a week
- Estimated price
- $130–220
- Website
- Amtrak
Train from Tucson Amtrak Station to Los Angeles
- Ave. Duration
- 10h 20m
- Frequency
- 6 times a week
- Estimated price
- $270–430
- Website
- Amtrak
Train from Los Angeles to San Diego Old Town Transportation Center
- Ave. Duration
- 2h 42m
- Frequency
- Hourly
- Estimated price
- $65–110
- Website
- Amtrak
- Phone
- +1 928-783-2235
- Website
- Yuma County Area Transit
Bus from 3rd Street @ Gila Street to 7th Street @ State Street
- Ave. Duration
- 1h 28m
- Frequency
- 6 times a week
- Estimated price
- $1–2
- Website
- Yuma County Area Transit
- Youth 5-18 w/ Student ID, Seniors 65+, Disabled
- $1
- Adults 19-64
- $2
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from El Centro Bus Stop to El Cajon Transit Center
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- $18–27
- Website
- Greyhound
Bus from Phoenix Bus Station to El Cajon Transit Center
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $60–95
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Tucson Downtown to Phoenix Sky Harbor Airport/44th Street Sky Train Station
- Ave. Duration
- 2h 10m
- Frequency
- 4 times a day
- Estimated price
- $18–27
- Schedules at
- Flixbus USA
- Phone
- +1 928-350-8466
- Website
- arizonashuttle.com
Bus from University of Phoenix to Sky Harbor International Airport
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- $50–90
- Book at
- Groome Transportation - Phoenix, AZ
- Phone
- +1 602 442 6802
- [email protected]
- Website
- Nenas Shuttle
Shuttle from Tucson to Puerto Peñasco
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $85
- Website
- Nenas Shuttle
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobuseselite.com.mx
Bus from Puerto Peñasco to Tijuana
- Ave. Duration
- 6h 7m
- Frequency
- Once daily
- Estimated price
- $45–70
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Want to know more about travelling around United States
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Booking & Getting There
Tucson to La Mesa bus services, operated by Flixbus USA, arrive at Phoenix Sky Harbor Airport/44th Street Sky Train Station.
Tucson to La Mesa train services, operated by Amtrak, arrive at Los Angeles station.
Yes, the driving distance between Tucson to La Mesa is 402 miles. It takes approximately 6h 19m to drive from Tucson to La Mesa.
There are 2051+ hotels available in La Mesa.





















