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How to get fromTupelo to Destinby bus, plane, taxi, car, or train

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There are 5 ways to get from Tupelo to Destin by bus, plane, taxi, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Memphis, fly

    best
    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Destin–Fort Walton Beach Airport (VPS)plane plane MEM - VPS
    8h 5m
    $147–555

  2. Drive  355 mi

    cheapest
    1. Drive from Tupelo to Destincar car 355 mi
    7h 57m
    $65–94

  3. Bus, taxi

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Mobilebus bus
    3. Take the bus from Loxley to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    15h 23m
    $249–342

  4. Bus to Hartsfield-Jackson Atlanta International Airport, fly

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Destin–Fort Walton Beach Airport (VPS)plane plane ATL - VPS
    8h 40m
    $144–492

  5. Bus, train, taxi

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Jacksonbus bus
    3. Take the train from Jackson to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Pascagoulatrain train
    5. Take the bus from Pascagoula to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    18h 59m
    $254–434

Memphis (MEM) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar46Weekly Planes
Duration4h 34mAverage Duration
Ticket$80Cheapest Price
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Comparing Your Travel Options

Map of how to get from Tupelo to Destin.ExpandLaunch map view
  • Distance: 493.2 mi
  • Duration: 8h 5m

What companies run services between Tupelo, MS, USA and Destin, FL, USA?

There is no direct connection from Tupelo to Destin. However, you can take the taxi to Tupelo, take the bus to Memphis Bus Station, take the line 28 bus to Memphis International Airport, walk to Memphis (MEM) airport, fly to Destin–Fort Walton Beach Airport (VPS), then take the taxi to Destin. Alternatively, you can take the taxi to Tupelo, take the bus to Atlanta Bus Station, walk to Garnett Station, take the subway to Doraville Station, walk to Atlanta, take the bus to Mobile, take the bus to Crestview, then take the taxi to Destin.

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