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How to get fromTupelo to Fort Myersby car, plane, bus (Greyhound, Flixbus), or bus

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There are 6 ways to get from Tupelo to Fort Myers by car, plane, bus (Greyhound, Flixbus), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Golden Triangle Regional Airport, fly

    best
    1. Drive from Tupelo to Golden Triangle Regional Airport (GTR)car car
    2. Fly from Golden Triangle Regional Airport (GTR) to Ft. Myers (RSW)plane plane GTR - RSW
    7h 19m
    $104–501

  2. Bus

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    19h 9m
    $124–229

  3. Drive 764.7 mi

    1. Drive from Tupelo to Fort Myerscar car 764.7 mi
    14h 21m
    $140–202

  4. Fly from Tupelo Regional Airport

    1. Fly from Tupelo Regional Airport (TUP) to Ft. Myers (RSW)plane plane TUP - RSW
    6h 31m
    $118–572

  5. Bus to Memphis, fly

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Ft. Myers (RSW)plane plane MEM - RSW
    9h 46m
    $149–697

  6. Bus via Tallahassee

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Fort Myersbus bus
    22h 30m
    $163–276

Golden Triangle Regional Airport (GTR) to Ft. Myers (RSW) flights

Calendar21Weekly Planes
Duration4h 58mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Tupelo to Fort Myers.ExpandLaunch map view
  • Distance: 705.6 mi
  • Duration: 7h 19m

What companies run services between Tupelo, MS, USA and Fort Myers, FL, USA?

You can take a vehicle from Tupelo to Fort Myers Bus Stop via Tupelo, Atlanta Bus Station, and Tampa Bus Station in around 19h 9m. Alternatively, Corporate Flight Management Inc, Southwest Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Ft. Myers (RSW) twice daily.

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Bus operators

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