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How to get fromTupelo to Fort Myersby car, plane, bus (Greyhound, Flixbus), or bus

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There are 8 ways to get from Tupelo to Fort Myers by car, plane, bus (Greyhound, Flixbus), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Golden Triangle Regional Airport, fly to Ft. Myers

    best
    1. Drive from Tupelo to Golden Triangle Regional Airport (GTR)car car
    2. Fly from Golden Triangle Regional Airport (GTR) to Ft. Myers (RSW)plane plane GTR - RSW
    8h 20m
    $99–441

  2. Bus via Gainesville

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    3. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Fort Myers 7-11bus bus
    19h 8m
    $181–333

  3. Drive 764.7 mi

    1. Drive from Tupelo to Fort Myerscar car 764.7 mi
    14h 21m
    $140–202

  4. Drive to Birmingham–Shuttlesworth International Airport, fly to Tampa, bus

    1. Drive from Tupelo to Birmingham-Airport-BHMcar car
    2. Fly from Birmingham–Shuttlesworth International Airport (BHM) to Tampa (TPA)plane plane BHM - TPA
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    8h 16m
    $125–532

  5. Fly Tupelo Regional Airport to Ft. Myers

    1. Fly from Tupelo Regional Airport (TUP) to Ft. Myers (RSW)plane plane TUP - RSW
    6h 31m
    $113–472

  6. Bus to Memphis, fly to Ft. Myers

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Ft. Myers (RSW)plane plane MEM - RSW
    9h 54m
    $151–650

  7. Bus

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    20h 4m
    $151–299

  8. Bus #2

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Fort Myersbus bus
    22h 30m
    $178–301

Golden Triangle Regional Airport (GTR) to Ft. Myers (RSW) flights

Calendar21Weekly Planes
Duration5h 32mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

Map of how to get from Tupelo to Fort Myers.ExpandLaunch map view
  • Distance: 705.6 mi
  • Duration: 8h 20m

What companies run services between Tupelo, MS, USA and Fort Myers, FL, USA?

You can take a vehicle from Tupelo to Fort Myers via Tupelo, Atlanta Bus Station, Gainesville, Rosa Parks RTS Downtown Station, UF Health Archer Road, University of Florida - 1956 Gale Lemerand Dr, and Fort Myers 7-11 in around 19h 8m. Alternatively, Corporate Flight Management Inc, Southwest Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Ft. Myers (RSW) 3 times a day.

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