There are 5 ways to get from Tupelo to Gainesville by bus (Greyhound, Flixbus), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Tupelo to Atlanta Bus Stationbus Greyhound US0610
- Take the bus from Atlanta Bus Station to Gainesvillebus FlixBus N2401 / ...
11h 54m$101–159Drive to Golden Triangle Regional Airport, fly
cheapest- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Gainesville Regional Airport (GNV)plane GTR - GNV
7h 26m$73–388Drive 538.4 mi
- Drive from Tupelo to Gainesvillecar 538.4 mi
9h 59m$99–142Drive to Huntsville International Airport-Carl T Jones Field, fly
- Drive from Tupelo to Huntsville International Airport-Carl T Jones Field (HSV)car
- Fly from Huntsville International Airport-Carl T Jones Field (HSV) to Gainesville Regional Airport (GNV)plane HSV - GNV
6h 48m$95–485Bus to Memphis, fly
- Take the bus from Tupelo to Memphis Bus Stationbus
- Fly from Memphis (MEM) to Gainesville Regional Airport (GNV)plane MEM - GNV
8h 51m$110–512
Golden Triangle Regional Airport (GTR) to Gainesville Regional Airport (GNV) flights
Comparing Your Travel Options
The cheapest way to get from Tupelo to Gainesville is to drive which costs $95 - $150 and takes 9h 59m.
The fastest way to get from Tupelo to Gainesville is to drive and fly which takes 6h 48m and costs $95 - $490.
No, there is no direct bus from Tupelo to Gainesville. However, there are services departing from Tupelo and arriving at Gainesville via Atlanta Bus Station. The journey, including transfers, takes approximately 11h 54m.
The distance between Tupelo and Gainesville is 613 miles. The road distance is 541.6 miles.
The best way to get from Tupelo to Gainesville without a car is to bus which takes 11h 54m and costs $100 - $160.
It takes approximately 11h 54m to get from Tupelo to Gainesville, including transfers.
Tupelo to Gainesville bus services, operated by Greyhound USA, depart from Tupelo station.
Tupelo to Gainesville bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Gainesville is 1h ahead of Tupelo. It is currently 10:10 PM in Tupelo and 11:10 PM in Gainesville.
Yes, the driving distance between Tupelo to Gainesville is 542 miles. It takes approximately 9h 59m to drive from Tupelo to Gainesville.
What companies run services between Tupelo, MS, USA and Gainesville, FL, USA?
You can take a vehicle from Tupelo to Gainesville via Tupelo and Atlanta Bus Station in around 11h 54m.
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Gainesville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $110–550
Flights from Huntsville International Airport-Carl T Jones Field to Gainesville Regional Airport via Charlotte
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $95–550
Flights from Huntsville International Airport-Carl T Jones Field to Gainesville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $150–700
Flights from Memphis to Gainesville Regional Airport via Charlotte
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $100–550
Flights from Memphis to Gainesville Regional Airport via Miami
- Ave. Duration
- 5h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Memphis to Gainesville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $130–650
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $16–25
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
Book your Tupelo to Gainesville bus tickets online with Omio.
There are 278+ hotels available in Gainesville.