What is the cheapest way to get from Tupelo to Indianapolis?

The cheapest way to get from Tupelo to Indianapolis is to drive which costs $85 - $130 and takes 9h 33m.

What is the fastest way to get from Tupelo to Indianapolis?

The fastest way to get from Tupelo to Indianapolis is to fly which takes 4h 54m and costs $95 - $490.

Is there a direct bus between Tupelo and Indianapolis?

No, there is no direct bus from Tupelo to Indianapolis station. However, there are services departing from Tupelo and arriving at Indianapolis Union Station via Memphis Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 13h 4m.

How far is it from Tupelo to Indianapolis?

The distance between Tupelo and Indianapolis is 640 miles. The road distance is 467.1 miles.

How do I travel from Tupelo to Indianapolis without a car?

The best way to get from Tupelo to Indianapolis without a car is to bus via St. Louis which takes 13h 4m and costs $100 - $200.

How long does it take to get from Tupelo to Indianapolis?

It takes approximately 13h 4m to get from Tupelo to Indianapolis, including transfers.

Where do I catch the Tupelo to Indianapolis bus from?

Tupelo to Indianapolis bus services, operated by Greyhound USA, depart from Tupelo station.

Bus or fly from Tupelo to Indianapolis?

The best way to get from Tupelo to Indianapolis is to bus via St. Louis which takes 13h 4m and costs $100 - $200. Alternatively, you can fly, which costs $95 - $490 and takes 4h 54m.

Where does the Tupelo to Indianapolis bus arrive?

Tupelo to Indianapolis bus services, operated by Greyhound USA, arrive at Memphis Bus Station.

What is the time difference between Tupelo and Indianapolis?

Indianapolis is 1h ahead of Tupelo. It is currently 10:18 PM in Tupelo and 11:18 PM in Indianapolis.

Can I drive from Tupelo to Indianapolis?

Yes, the driving distance between Tupelo to Indianapolis is 467 miles. It takes approximately 9h 33m to drive from Tupelo to Indianapolis.

How do I get a bus ticket from Tupelo to Indianapolis?

Book your Tupelo to Indianapolis bus tickets online with Omio.

Where can I stay near Indianapolis?

There are 775+ hotels available in Indianapolis.

Tupelo to Indianapolis - 7 ways to travel via bus, car, and plane

How to get fromTupelo to Indianapolis

Travel from

See all options

Search accommodation with Expedia

There are 7 ways to get from Tupelo to Indianapolis by bus (Greyhound, Flixbus), car, plane, bus (Greyhound, Flixbus, Amtrak), bus (Greyhound), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus via St. Louis
best
1. Take the bus from Tupelo to Memphis Bus Stationbus
2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus
3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
13h 4m
$106–198
Drive 464.4 mi
cheapest
1. Drive from Tupelo to Indianapoliscar 464.4 mi
9h 33m
$85–123
Drive to Golden Triangle Regional Airport, fly
1. Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
2. Fly from Golden Triangle Regional Airport (GTR) to Indianapolis (IND)plane GTR - IND
7h 51m
$113–568
Bus
1. Take the bus from Tupelo to Memphis Bus Stationbus
2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus
3. Take the bus from Nashville Bus Station to Indianapolis Union Stationbus
13h 34m
$101–163
Bus #2
1. Take the bus from Tupelo to Memphis Bus Stationbus Greyhound US0610
2. Take the bus from Tornado Bus Co - West Memphis to Indianapolisbus Memphis
14h 50m
$139–281
Fly from Tupelo Regional Airport
1. Fly from Tupelo Regional Airport (TUP) to Indianapolis (IND)plane TUP - IND
4h 54m
$97–489
Bus to Memphis, fly
1. Take the bus from Tupelo to Memphis Bus Stationbus
2. Fly from Memphis (MEM) to Indianapolis (IND)plane MEM - IND
8h 18m
$139–696

Golden Triangle Regional Airport (GTR) to Indianapolis (IND) flights

21Weekly Planes

6h 11mAverage Duration

$104Cheapest Price

See schedules

Questions & Answers

Map of how to get from Tupelo to Indianapolis.

Launch map view

Distance: 636.8 mi
Duration: 13h 4m

What companies run services between Tupelo, MS, USA and Indianapolis, IN, USA?

You can take a vehicle from Tupelo to Indianapolis Union Station via Tupelo, Memphis Bus Station, and St Louis Bus Station in around 13h 4m. Alternatively, Corporate Flight Management Inc, Southwest Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Indianapolis (IND) once daily.

Airlines

Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.