There are 6 ways to get from Tupelo to Lake Charles by car, plane, bus (Greyhound, Flixbus), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Golden Triangle Regional Airport, fly
best- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Lake Charles Regional Airport (LCH)plane GTR - LCH
8h 21m$102–429Drive 435.1 mi
cheapest- Drive from Tupelo to Lake Charlescar 435.1 mi
9h 49m$80–115Bus
- Take the bus from Tupelo to Memphis Bus Stationbus Greyhound US0610
- Take the bus from Memphis Bus Station to Lake Charlesbus FlixBus N2211
14h 24m$127–214Fly from Tupelo Regional Airport
- Fly from Tupelo Regional Airport (TUP) to Lake Charles Regional Airport (LCH)plane TUP - LCH
7h 45m$116–470Bus to Memphis, fly
- Take the bus from Tupelo to Memphis Bus Stationbus
- Fly from Memphis (MEM) to Lake Charles Regional Airport (LCH)plane MEM - LCH
8h 38m$129–538Bus via Baton Rouge
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Baton Rouge Bus Stationbus
- Take the bus from Baton Rouge Bus Station to Lake Charlesbus
16h 29m$122–234
Golden Triangle Regional Airport (GTR) to Lake Charles Regional Airport (LCH) flights
Questions & Answers
The cheapest way to get from Tupelo to Lake Charles is to drive which costs $75 - $120 and takes 9h 49m.
The fastest way to get from Tupelo to Lake Charles is to fly which takes 7h 45m and costs $110 - $470.
No, there is no direct bus from Tupelo to Lake Charles. However, there are services departing from Tupelo and arriving at Lake Charles via Memphis Bus Station. The journey, including transfers, takes approximately 14h 24m.
The distance between Tupelo and Lake Charles is 428 miles. The road distance is 437.7 miles.
The best way to get from Tupelo to Lake Charles without a car is to bus which takes 14h 24m and costs $120 - $220.
It takes approximately 8h 21m to get from Tupelo to Lake Charles, including transfers.
Tupelo to Lake Charles bus services, operated by Greyhound USA, depart from Tupelo station.
The best way to get from Tupelo to Lake Charles is to bus which takes 14h 24m and costs $120 - $220. Alternatively, you can fly, which costs $110 - $470 and takes 7h 45m.
Tupelo to Lake Charles bus services, operated by Greyhound USA, arrive at Memphis Bus Station.
Yes, the driving distance between Tupelo to Lake Charles is 438 miles. It takes approximately 9h 49m to drive from Tupelo to Lake Charles.
What companies run services between Tupelo, MS, USA and Lake Charles, LA, USA?
You can take a vehicle from Tupelo to Lake Charles via Tupelo and Memphis Bus Station in around 14h 24m. Alternatively, Corporate Flight Management Inc, American Airlines, and United Airlines fly from Tupelo Regional Airport (TUP) to Lake Charles Regional Airport (LCH) 3 times a day.
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Lake Charles Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $80–400
Flights from Tupelo Regional Airport to Lake Charles Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 42m
- When
- Every day
- Estimated price
- $190–800
Flights from Tupelo Regional Airport to Lake Charles Regional Airport via Nashville, Dallas/Ft.Worth
- Ave. Duration
- 8h 27m
- When
- Every day
- Estimated price
- $100–470
Flights from Memphis to Lake Charles Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $100–550
- Website
- united.com
Flights from Tupelo Regional Airport to Lake Charles Regional Airport via Nashville, Houston
- Ave. Duration
- 9h 42m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- $90–440
Flights from Tupelo Regional Airport to Lake Charles Regional Airport via Dallas/Ft.Worth, Houston
- Ave. Duration
- 12h 16m
- When
- Sunday
- Estimated price
- $200–800
Flights from Memphis to Lake Charles Regional Airport via Houston
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $90–480
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $16–30
- Website
- https://www.greyhound.com/
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $16–30
- Website
- https://www.greyhound.com/
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $16–30
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Baton Rouge Bus Station
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- $75–150
- Website
- https://www.greyhound.com/
Bus from Baton Rouge Bus Station to Lake Charles
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Memphis Bus Station to Lake Charles
- Ave. Duration
- 11h 30m
- Frequency
- 5 times a week
- Estimated price
- $100–170
- Schedules at
- flixbus.com
Bus from Memphis Bus Station to Baton Rouge Bus Station
- Ave. Duration
- 9h 30m
- Frequency
- 5 times a week
- Estimated price
- $75–130
- Schedules at
- flixbus.com
Bus from Baton Rouge Bus Station to Lake Charles
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $20–35
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Book your Tupelo to Lake Charles bus tickets online with Omio.
There are 121+ hotels available in Lake Charles.



