There are 5 ways to get from Tupelo to Lake Charles by car, plane, bus (Greyhound, Flixbus), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Golden Triangle Regional Airport, fly
best- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Lake Charles Regional Airport (LCH)plane GTR - LCH
8h 22m$97–449Drive 435.1 mi
cheapest- Drive from Tupelo to Lake Charlescar 435.1 mi
9h 49m$80–115Bus
- Take the bus from Tupelo to Memphis Bus Stationbus Greyhound US0610
- Take the bus from Memphis Bus Station to Lake Charlesbus FlixBus N2211
14h 24m$121–189Bus to Memphis, fly
- Take the bus from Tupelo to Memphis Bus Stationbus
- Fly from Memphis (MEM) to Lake Charles Regional Airport (LCH)plane MEM - LCH
8h 13m$118–513Bus via Baton Rouge
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Baton Rouge Bus Stationbus
- Take the bus from Baton Rouge Bus Station to Lake Charlesbus
16h 29m$114–204
Golden Triangle Regional Airport (GTR) to Lake Charles Regional Airport (LCH) flights
Comparing Your Travel Options
The cheapest way to get from Tupelo to Lake Charles is to drive which costs $75 - $120 and takes 9h 49m.
The fastest way to get from Tupelo to Lake Charles is to bus and fly which takes 8h 13m and costs $110 - $550.
No, there is no direct bus from Tupelo to Lake Charles. However, there are services departing from Tupelo and arriving at Lake Charles via Memphis Bus Station. The journey, including transfers, takes approximately 14h 24m.
The distance between Tupelo and Lake Charles is 428 miles. The road distance is 437.7 miles.
The best way to get from Tupelo to Lake Charles without a car is to bus which takes 14h 24m and costs $120 - $190.
It takes approximately 8h 22m to get from Tupelo to Lake Charles, including transfers.
Tupelo to Lake Charles bus services, operated by Greyhound USA, depart from Tupelo station.
Tupelo to Lake Charles bus services, operated by Greyhound USA, arrive at Memphis Bus Station.
Yes, the driving distance between Tupelo to Lake Charles is 438 miles. It takes approximately 9h 49m to drive from Tupelo to Lake Charles.
Book your Tupelo to Lake Charles bus tickets online with Omio.
What companies run services between Tupelo, MS, USA and Lake Charles, LA, USA?
You can take a vehicle from Tupelo to Lake Charles via Tupelo and Memphis Bus Station in around 14h 24m.
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Lake Charles Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 1m
- When
- Every day
- Estimated price
- $75–420
Flights from Memphis to Lake Charles Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $90–490
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Memphis Bus Station to Baton Rouge Bus Station
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- $75–130
- Website
- Greyhound
Bus from Baton Rouge Bus Station to Lake Charles
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $19–35
- Website
- Greyhound
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Booking & Getting There
There are 132+ hotels available in Lake Charles.


