Rome2Rio

How to get fromTupelo to Lexingtonby car, plane, or bus

Find Transport to Lexington

See all options

There are 7 ways to get from Tupelo to Lexington by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Golden Triangle Regional Airport, fly to Blue Grass Airport

    best
    1. Drive from Tupelo to Golden Triangle Regional Airport (GTR)car car
    2. Fly from Golden Triangle Regional Airport (GTR) to Blue Grass Airport (LEX)plane plane GTR - LEX
    7h 20m
    $143–818

  2. Drive 412.1 mi

    cheapest
    1. Drive from Tupelo to Lexingtoncar car 412.1 mi
    8h
    $76–109

  3. Bus, drive via Brentwood

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    15h 23m
    $105–186

  4. Fly Tupelo Regional Airport to Louisville International Airport, drive

    1. Fly from Tupelo Regional Airport (TUP) to Louisville International Airport (SDF)plane plane TUP - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    4h 58m
    $189–638

  5. Fly Tupelo Regional Airport to Covington, drive

    1. Fly from Tupelo Regional Airport (TUP) to Covington (CVG)plane plane TUP - CVG
    2. Drive from Covington (CVG) to Lexingtoncar car
    5h 9m
    $110–539

  6. Bus to Memphis, fly to Blue Grass Airport

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Blue Grass Airport (LEX)plane plane MEM - LEX
    9h 45m
    $218–1,146

  7. Bus, drive

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    4. Drive from Middletown Station @ Target to Lexingtoncar car
    16h 17m
    $98–174

Golden Triangle Regional Airport (GTR) to Blue Grass Airport (LEX) flights

Calendar35Weekly Planes
Duration6h 8mAverage Duration
Ticket$136Cheapest Price
See schedules

Questions & Answers

Map of how to get from Tupelo to Lexington.ExpandLaunch map view
  • Distance: 463.8 mi
  • Duration: 7h 20m

What companies run services between Tupelo, MS, USA and Lexington, KY, USA?

There is no direct connection from Tupelo to Lexington. However, you can drive to Golden Triangle Regional Airport (GTR) airport, fly to Blue Grass Airport (LEX), walk to Terminal @ Bluegrass Field, take the line 8 bus to Transit Center, then take the line 3 bus to Centre Parkway @ 1349. Alternatively, you can take a vehicle from Tupelo to Lexington via Tupelo, Memphis Bus Station, Nashville Bus Station, Fulton Station Outbound, Walmart Station Outbound, Tornado Bus Co - Nashville, La Tropicana - Louisville, KY, Preston @ Vim, S 5th @ W Jefferson, and Middletown Station @ Target in around 15h 23m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound