Rome2Rio

How to get fromTupelo to Panama Cityby car, plane, or bus

Find Transport to Panama City

See all options

There are 4 ways to get from Tupelo to Panama City by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Golden Triangle Regional Airport, fly

    best
    1. Drive from Tupelo to Golden Triangle Regional Airport (GTR)car car
    2. Fly from Golden Triangle Regional Airport (GTR) to Northwest Florida Beaches International Airport (ECP)plane plane GTR - ECP
    5h 18m
    $136–436

  2. Drive 390.6 mi

    cheapest
    1. Drive from Tupelo to Panama Citycar car 390.6 mi
    7h 22m
    $72–103

  3. Bus, drive

    1. Take the bus from Tupelo to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to La Grange Bus Stationbus bus
    3. Take the bus from La Grange Bus Station to Mobilebus bus
    4. Take the bus from Loxley to Crestviewbus bus
    5. Drive from Crestview to Front Beach Rd. & Back Beach Rd.car car
    19h 6m
    $185–278

  4. Fly from Tupelo Regional Airport

    1. Fly from Tupelo Regional Airport (TUP) to Northwest Florida Beaches International Airport (ECP)plane plane TUP - ECP
    4h 2m
    $145–457

Golden Triangle Regional Airport (GTR) to Northwest Florida Beaches International Airport (ECP) flights

Calendar18Weekly Planes
Duration4h 46mAverage Duration
Ticket$60Cheapest Price
See schedules

Questions & Answers

Map of how to get from Tupelo to Panama City.ExpandLaunch map view
  • Distance: 354.2 mi
  • Duration: 5h 18m

What companies run services between Tupelo, MS, USA and Panama City, FL, USA?

Corporate Flight Management Inc, Southwest Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Northwest Florida Beaches International Airport (ECP) twice daily.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound