There are 6 ways to get from Tupelo to Pensacola by car, plane, bus (Greyhound), taxi, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Golden Triangle Regional Airport, fly to Pensacola International Airport
best- Drive from Tupelo to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Pensacola International Airport (PNS)plane GTR - PNS
8h 15m$58–308Bus
- Take the bus from Tupelo to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to La Grange Bus Stationbus
- Take the bus from La Grange Bus Station to Mobilebus
- Take the bus from Loxley to Pensacolabus
13h 58m$177–246Drive 331 mi
- Drive from Tupelo to Pensacolacar 331 mi
6h 25m$61–88Fly Tupelo Regional Airport to Pensacola International Airport
- Fly from Tupelo Regional Airport (TUP) to Pensacola International Airport (PNS)plane TUP - PNS
6h 42m$67–319Fly Tupelo Regional Airport to Destin–Fort Walton Beach Airport, taxi
- Fly from Tupelo Regional Airport (TUP) to Destin–Fort Walton Beach Airport (VPS)plane TUP - VPS
- Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi
6h 58m$200–537Bus, train
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Jacksonbus
- Take the train from Jackson to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Pascagoulatrain
- Take the bus from Pascagoula to Pensacolabus
17h 24m$259–406
Golden Triangle Regional Airport (GTR) to Pensacola International Airport (PNS) flights
Comparing Your Travel Options
The cheapest way to get from Tupelo to Pensacola is to drive which costs $60 - $90 and takes 6h 25m.
The fastest way to get from Tupelo to Pensacola is to drive which takes 6h 25m and costs $60 - $90.
No, there is no direct bus from Tupelo to Pensacola. However, there are services departing from Tupelo and arriving at Pensacola via Atlanta Bus Station, La Grange Bus Station and Loxley. The journey, including transfers, takes approximately 13h 58m.
The distance between Tupelo and Pensacola is 289 miles. The road distance is 332.9 miles.
The best way to get from Tupelo to Pensacola without a car is to bus which takes 13h 58m and costs $170 - $250.
It takes approximately 8h 15m to get from Tupelo to Pensacola, including transfers.
Tupelo to Pensacola bus services, operated by Greyhound USA, depart from Tupelo station.
The best way to get from Tupelo to Pensacola is to bus which takes 13h 58m and costs $170 - $250. Alternatively, you can fly, which costs $65 - $320 and takes 6h 42m.
Tupelo to Pensacola bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Tupelo to Pensacola is 333 miles. It takes approximately 6h 25m to drive from Tupelo to Pensacola.
What companies run services between Tupelo, MS, USA and Pensacola, FL, USA?
You can take a vehicle from Tupelo to Pensacola via Tupelo, Atlanta Bus Station, La Grange Bus Station, and Loxley in around 13h 58m. Alternatively, Corporate Flight Management Inc, American Airlines, and two other airlines fly from Tupelo Regional Airport (TUP) to Pensacola International Airport (PNS) twice daily.
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Pensacola International Airport via Atlanta
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $45–290
Flights from Tupelo Regional Airport to Pensacola International Airport via Nashville, Atlanta
- Ave. Duration
- 6h 57m
- When
- Every day
- Estimated price
- $55–310
Flights from Tupelo Regional Airport to Destin–Fort Walton Beach Airport via Nashville, Atlanta
- Ave. Duration
- 8h
- When
- Every day
- Estimated price
- $65–390
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Pensacola International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $75–380
Flights from Tupelo Regional Airport to Pensacola International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 47m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $75–380
Flights from Tupelo Regional Airport to Destin–Fort Walton Beach Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 54m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $95–480
- Website
- southwest.com
Flights from Tupelo Regional Airport to Pensacola International Airport via Nashville
- Ave. Duration
- 5h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $50–300
Flights from Tupelo Regional Airport to Destin–Fort Walton Beach Airport via Nashville
- Ave. Duration
- 6h 17m
- When
- Sunday and Saturday
- Estimated price
- $65–370
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jackson to New Orleans Union Passenger Terminal
- Ave. Duration
- 3h 58m
- Frequency
- Once daily
- Estimated price
- $100–160
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Pascagoula
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $50–85
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Website
- Greyhound
Bus from Atlanta Bus Station to La Grange Bus Station
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $11–17
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $18–27
- Website
- Greyhound
Bus from Memphis Bus Station to Jackson
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- Greyhound
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from La Grange Bus Station to Mobile
- Ave. Duration
- 3h 32m
- Frequency
- Once daily
- Estimated price
- $65–85
- Schedules at
- Omnibus Express
Bus from Loxley to Pensacola
- Ave. Duration
- 37 min
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- Omnibus Express
Bus from Pascagoula to Pensacola
- Ave. Duration
- 1h 36m
- Frequency
- Once daily
- Estimated price
- $45–60
- Schedules at
- Omnibus Express
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Book your Tupelo to Pensacola bus tickets online with Omio.
There are 1556+ hotels available in Pensacola.







