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How to get fromTupelo to San Antonioby car, plane, bus (Greyhound, Flixbus), bus, or bus (Greyhound)

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There are 7 ways to get from Tupelo to San Antonio by car, plane, bus (Greyhound, Flixbus), bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Golden Triangle Regional Airport, fly

    best
    1. Drive from Tupelo to Golden Triangle Regional Airport (GTR)car car
    2. Fly from Golden Triangle Regional Airport (GTR) to San Antonio International Airport (SAT)plane plane GTR - SAT
    7h
    $108–567

  2. Bus via Irving

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to San Antonio Bus Stationbus bus
    17h 44m
    $149–251

  3. Drive  763 mi

    1. Drive from Tupelo to San Antoniocar car 763 mi
    14h 36m
    $131–189

  4. Bus to Memphis, fly

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to San Antonio International Airport (SAT)plane plane MEM - SAT
    6h 54m
    $142–694

  5. Fly from Tupelo Regional Airport

    1. Fly from Tupelo Regional Airport (TUP) to San Antonio International Airport (SAT)plane plane TUP - SAT
    5h 1m
    $127–619

  6. Bus

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus Greyhound US0610
    2. Take the bus from Tornado Bus Co - West Memphis to Tornado Bus Co - San Antoniobus bus West Memphis / ...
    18h 17m
    $221–353

  7. Bus #2

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Downtown Houstonbus bus
    3. Take the bus from Houston Bus Station to San Antonio Bus Stationbus bus
    21h 50m
    $179–286

Golden Triangle Regional Airport (GTR) to San Antonio International Airport (SAT) flights

Calendar21Weekly Planes
Duration5h 37mAverage Duration
Ticket$95Cheapest Price
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Comparing Your Travel Options

Map of how to get from Tupelo to San Antonio.ExpandLaunch map view
  • Distance: 712.7 mi
  • Duration: 7h

What companies run services between Tupelo, MS, USA and San Antonio, TX, USA?

You can take a vehicle from Tupelo to San Antonio Bus Station via Tupelo, Memphis Bus Station, and Dallas Bus Station in around 17h 44m. Alternatively, Corporate Flight Management Inc, American Airlines, and Southwest Airlines fly from Tupelo Regional Airport (TUP) to San Antonio International Airport (SAT) twice daily.

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Bus operators

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