Rome2Rio

How to get fromTupelo to Sedaliaby bus, train, car, plane, or bus (Greyhound, Flixbus)

Find Transport to Sedalia

See all options

There are 6 ways to get from Tupelo to Sedalia by bus, train, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Sedalia Amtrak Stationtrain train
    12h 41m
    $174–281
  2. Drive  470.1 mi

    cheapest
    1. Drive from Tupelo to Sedaliacar car 470.1 mi
    9h 7m
    $86–124
  3. Fly to Columbia Regional Airport, drive

    1. Fly from Tupelo Regional Airport (TUP) to Columbia Regional Airport (COU)plane plane TUP - COU
    2. Drive from Columbia Regional Airport (COU) to Sedaliacar car
    7h 55m
    $114–479
  4. Bus

    1. Take the bus from Tupelo to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to La Montebus bus
    14h 47m
    $154–236
  5. Fly to Lambert–St. Louis International Airport, train

    1. Fly from Tupelo Regional Airport (TUP) to Lambert–St. Louis International Airport (STL)plane plane TUP - STL
    2. Take the train from St. Louis to Sedalia Amtrak Stationtrain train
    10h 23m
    $193–650
  6. Fly to Kansas City, train

    1. Fly from Tupelo Regional Airport (TUP) to Kansas City (MCI)plane plane TUP - MCI
    2. Take the train from Kansas City to Sedalia Amtrak Stationtrain train
    9h 29m
    $165–697

Tupelo Regional Airport (TUP) to Columbia Regional Airport (COU) flights

Calendar9Weekly Planes
Duration7h 58mAverage Duration
Ticket$85Cheapest Price
See schedules

Comparing Your Travel Options

What companies run services between Tupelo, MS, USA and Sedalia, MO, USA?

You can take a vehicle from Tupelo to Sedalia via Tupelo, Memphis Bus Station, St Louis Bus Station, and La Monte in around 14h 47m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There