There are 3 ways to get from Tupelo to Sedalia by bus, train, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to St Louis Bus Stationbus
- Take the train from St. Louis to Sedalia Amtrak Stationtrain
12h 41m$111–224Drive 470.1 mi
cheapest- Drive from Tupelo to Sedaliacar 470.1 mi
9h 7m$86–124Bus
- Take the bus from Tupelo to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to La Montebus
14h 47m$141–224
Comparing Your Travel Options
The cheapest way to get from Tupelo to Sedalia is to drive which costs $85 - $130 and takes 9h 7m.
The fastest way to get from Tupelo to Sedalia is to drive which takes 9h 7m and costs $85 - $130.
No, there is no direct bus from Tupelo to Sedalia. However, there are services departing from Tupelo and arriving at La Monte via Memphis Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 14h 47m.
The distance between Tupelo and Sedalia is 584 miles. The road distance is 472.8 miles.
The best way to get from Tupelo to Sedalia without a car is to bus and train which takes 12h 41m and costs $110 - $230.
It takes approximately 12h 41m to get from Tupelo to Sedalia, including transfers.
Tupelo to Sedalia bus services, operated by Greyhound USA, depart from Tupelo station.
Tupelo to Sedalia bus services, operated by Greyhound USA, arrive at Memphis Bus Station.
Yes, the driving distance between Tupelo to Sedalia is 473 miles. It takes approximately 9h 7m to drive from Tupelo to Sedalia.
Book your Tupelo to Sedalia bus tickets online with Omio.
What companies run services between Tupelo, MS, USA and Sedalia, MO, USA?
You can take a vehicle from Tupelo to Sedalia via Tupelo, Memphis Bus Station, St Louis Bus Station, and La Monte in around 14h 47m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Sedalia Amtrak Station
- Ave. Duration
- 3h 32m
- Frequency
- Twice daily
- Estimated price
- $45–110
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Memphis Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Tupelo to Memphis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Memphis Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from St Louis Bus Station to La Monte
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- Greyhound
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Booking & Getting There
There are 18+ hotels available in Sedalia.






