What is the cheapest way to get from Tupelo to Sikeston?

The cheapest way to get from Tupelo to Sikeston is to drive which costs $40 - $60 and takes 4h 12m.

What is the fastest way to get from Tupelo to Sikeston?

The fastest way to get from Tupelo to Sikeston is to drive which takes 4h 12m and costs $40 - $60.

Is there a direct bus between Tupelo and Sikeston?

No, there is no direct bus from Tupelo to Sikeston. However, there are services departing from Tupelo and arriving at Flying J - Matthews via Tornado Bus Co - West Memphis. The journey, including transfers, takes approximately 5h 46m.

How far is it from Tupelo to Sikeston?

The distance between Tupelo and Sikeston is 256 miles. The road distance is 227.3 miles.

How do I travel from Tupelo to Sikeston without a car?

The best way to get from Tupelo to Sikeston without a car is to bus which takes 5h 46m and costs $120 - $190.

How long does it take to get from Tupelo to Sikeston?

It takes approximately 5h 46m to get from Tupelo to Sikeston, including transfers.

Where do I catch the Tupelo to Sikeston bus from?

Tupelo to Sikeston bus services, operated by Greyhound USA, depart from Tupelo station.

Where does the Tupelo to Sikeston bus arrive?

Tupelo to Sikeston bus services, operated by Greyhound USA, arrive at Memphis Bus Station.

Can I drive from Tupelo to Sikeston?

Yes, the driving distance between Tupelo to Sikeston is 227 miles. It takes approximately 4h 12m to drive from Tupelo to Sikeston.

Where can I stay near Sikeston?

There are 12+ hotels available in Sikeston.

Tupelo to Sikeston - 2 ways to travel via bus, and car

How to get fromTupelo to Sikeston

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There are 2 ways to get from Tupelo to Sikeston by bus (Greyhound) or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus
best
1. Take the bus from Tupelo to Memphis Bus Stationbus Greyhound US0610
2. Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus Milwaukee
5h 46m
$120–181
Drive 225.9 mi
cheapest
1. Drive from Tupelo to Sikestoncar 225.9 mi
4h 12m
$42–60

Questions & Answers

Map of how to get from Tupelo to Sikeston.

Launch map view

Distance: 254.1 mi
Duration: 5h 46m

What companies run services between Tupelo, MS, USA and Sikeston, MO, USA?

You can take a vehicle from Tupelo to Sikeston via Tupelo, Memphis Bus Station, Tornado Bus Co - West Memphis, and Flying J - Matthews in around 5h 46m.

Operators

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