There are 2 ways to get from Tupelo to Tuscaloosa by bus (Greyhound) or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Comparing Your Travel Options
The cheapest way to get from Tupelo to Tuscaloosa is to drive which costs $21 - $35 and takes 2h 18m.
The fastest way to get from Tupelo to Tuscaloosa is to drive which takes 2h 18m and costs $21 - $35.
No, there is no direct bus from Tupelo to Tuscaloosa. However, there are services departing from Tupelo and arriving at Tuscaloosa Bus Stop via Atlanta Bus Station. The journey, including transfers, takes approximately 10h 44m.
The distance between Tupelo and Tuscaloosa is 483 miles. The road distance is 119.5 miles.
The best way to get from Tupelo to Tuscaloosa without a car is to bus which takes 10h 44m and costs $80 - $140.
It takes approximately 10h 44m to get from Tupelo to Tuscaloosa, including transfers.
Tupelo to Tuscaloosa bus services, operated by Greyhound USA, depart from Tupelo station.
Tupelo to Tuscaloosa bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Tupelo to Tuscaloosa is 119 miles. It takes approximately 2h 18m to drive from Tupelo to Tuscaloosa.
Book your Tupelo to Tuscaloosa bus tickets online with Omio.
What companies run services between Tupelo, MS, USA and Tuscaloosa, AL, USA?
You can take a vehicle from Tupelo to Tuscaloosa Bus Stop via Tupelo and Atlanta Bus Station in around 10h 44m.
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tupelo to Atlanta Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Atlanta Bus Station to Tuscaloosa Bus Stop
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $30–50
- Website
- Greyhound
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Booking & Getting There
There are 126+ hotels available in Tuscaloosa.


