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How to get fromTupiza to Santiagoby bus, plane, car, or train

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There are 7 ways to get from Tupiza to Santiago by bus, plane, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Tarija, fly

    best
    1. Take the bus from Tupiza to Tarijabus bus
    2. Fly from Tarija (TJA) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane TJA - SCL
    14h 57m
    $387–725

  2. Train, bus

    cheapest
    1. Take the train from Tupiza to Villazóntrain train
    2. Take the bus from Terminal La Quiaca to Terminal Mendozabus bus
    3. Take the bus from Terminal Mendoza to Terminal Sur de Santiagobus bus
    46h 40m
    $87–178

  3. Bus

    1. Take the bus from Tupiza to Uyunibus bus
    2. Take the bus from Uyuni to Terminal de Buses Calamabus bus
    3. Take the bus from Terminal de Buses Calama to Terminal San Borjabus bus
    32h 44m
    $110–155

  4. Drive 1,978.7 km

    1. Drive from Tupiza to Santiagocar car 1,978.7 km
    25h 4m
    $244–353

  5. Bus to Alcantari Airport, fly

    1. Take the bus from Tupiza to Sucrebus bus
    2. Fly from Alcantari Airport (SRE) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane SRE - SCL
    11h 52m
    $436–756

  6. Bus, bus to Calama Airport, fly

    1. Take the bus from Tupiza to Uyunibus bus
    2. Take the bus from Uyuni to Terminal de Buses Calamabus bus
    3. Fly from Calama Airport (CJC) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane CJC - SCL
    15h 18m
    $109–257

  7. Train, bus via Calama

    1. Take the train from Tupiza to Uyunítrain train
    2. Take the bus from Uyuni to Terminal Rodoviario Calamabus bus
    3. Take the bus from Calama to Santiagobus bus
    38h 45m
    $190–312

Tupiza to Santiago by train, car, and bus

Calendar1Weekly Services
Duration46h 40mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

Map of how to get from Tupiza to Santiago.ExpandLaunch map view
  • Distance: 1,672.9 km
  • Duration: 14h 57m

What companies run services between Tupiza, Bolivia and Santiago, Chile?

You can take a bus from Tupiza to Terminal San Borja via Uyuni, Uyuni, and Terminal de Buses Calama in around 32h 44m.

Airlines
Train operators
Bus operators

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