There are 9 ways to get from Tuscaloosa to Des Moines by bus, plane, bus (Greyhound), train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Birmingham–Shuttlesworth International Airport, fly
best- Take the bus from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Birmingham-Shuttlesworthbus
- Fly from Birmingham–Shuttlesworth International Airport (BHM) to Des Moines (DSM)plane BHM - DSM
6h 26m$136–486Drive to Golden Triangle Regional Airport, fly
cheapest- Drive from Tuscaloosa to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Des Moines (DSM)plane GTR - DSM
6h 16m$115–490Bus
- Take the bus from Tuscaloosa Bus Stop to Jacksonbus
- Take the bus from Jackson to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Kansas City Bus Stationbus
- Take the bus from Kansas City to Des Moinesbus
24h$218–334Bus, train
- Take the bus from Tuscaloosa Bus Stop to Jacksonbus
- Take the train from Jackson to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Des Moinesbus
25h 55m$433–694Drive 788.9 mi
- Drive from Tuscaloosa to Des Moinescar 788.9 mi
15h 7m$135–195Drive to Montgomery Regional Airport, fly
- Drive from Tuscaloosa to Montgomery-Airport-MGMcar
- Fly from Montgomery Regional Airport (MGM) to Des Moines (DSM)plane MGM - DSM
6h 37m$116–479Drive to Huntsville International Airport-Carl T Jones Field, fly
- Drive from Tuscaloosa to Huntsville International Airport-Carl T Jones Field (HSV)car
- Fly from Huntsville International Airport-Carl T Jones Field (HSV) to Des Moines (DSM)plane HSV - DSM
6h 56m$116–476Bus to Hartsfield-Jackson Atlanta International Airport, fly
- Take the bus from Tuscaloosa Bus Stop to Atlanta Bus Stationbus
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Des Moines (DSM)plane ATL - DSM
8h 35m$138–521Bus via Wake Village
- Take the bus from Tuscaloosa Bus Stop to Shreveport Bus Stationbus
- Take the bus from Shreveport Bus Station to Texarkanabus
- Take the bus from Texarkana to Kansas Citybus
- Take the bus from Kansas City to Des Moinesbus
25h 40m$247–364
Tuscaloosa to Des Moines by bus
Comparing Your Travel Options
The cheapest way to get from Tuscaloosa to Des Moines is to drive which costs $130 - $200 and takes 15h 7m.
The fastest way to get from Tuscaloosa to Des Moines is to drive and fly which takes 6h 16m and costs $110 - $490.
No, there is no direct bus from Tuscaloosa to Des Moines. However, there are services departing from Tuscaloosa Bus Stop and arriving at Des Moines via Jackson, St Louis Bus Station and Kansas City. The journey, including transfers, takes approximately 24h.
The distance between Tuscaloosa and Des Moines is 741 miles. The road distance is 793.5 miles.
The best way to get from Tuscaloosa to Des Moines without a car is to bus which takes 24h and costs $210 - $340.
It takes approximately 6h 26m to get from Tuscaloosa to Des Moines, including transfers.
Tuscaloosa to Des Moines bus services, operated by Greyhound USA, depart from Tuscaloosa Bus Stop station.
Tuscaloosa to Des Moines bus services, operated by Greyhound USA, arrive at Jackson station.
Yes, the driving distance between Tuscaloosa to Des Moines is 794 miles. It takes approximately 15h 7m to drive from Tuscaloosa to Des Moines.
Book your Tuscaloosa to Des Moines bus tickets online with Omio.
What companies run services between Tuscaloosa, AL, USA and Des Moines, IA, USA?
You can take a bus from Tuscaloosa Bus Stop to Des Moines via Jackson, St Louis Bus Station, Kansas City Bus Station, and Kansas City in around 24h.
- Website
- delta.com
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $80–430
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Detroit
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $95–480
Flights from Golden Triangle Regional Airport to Des Moines via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 6h 54m
- When
- Every day
- Estimated price
- $85–450
Flights from Montgomery Regional Airport to Des Moines via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $80–430
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $80–430
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Detroit
- Ave. Duration
- 6h 28m
- When
- Every day
- Estimated price
- $95–470
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $80–440
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Minneapolis
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $100–550
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Detroit
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $100–550
- Website
- aa.com
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $100–490
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $95–480
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 28m
- When
- Every day
- Estimated price
- $80–430
Flights from Golden Triangle Regional Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $95–470
Flights from Montgomery Regional Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $100–490
Flights from Montgomery Regional Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $100–480
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $100–490
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Charlotte
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $95–480
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 52m
- When
- Every day
- Estimated price
- $75–420
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 3m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $100–500
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $90–470
- Website
- united.com
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Houston
- Ave. Duration
- 6h 42m
- When
- Every day
- Estimated price
- $110–550
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $80–430
Flights from Montgomery Regional Airport to Des Moines via Houston
- Ave. Duration
- 5h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $75–420
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Houston
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $110–550
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $90–470
- Website
- southwest.com
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Nashville
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $70–400
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 5h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–430
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Nashville
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–440
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $90–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jackson to Champaign-Urbana
- Ave. Duration
- 12h 45m
- Frequency
- Once daily
- Estimated price
- $340–550
- Website
- Amtrak
- Phone
- +1 (205) 719-0469
- [email protected]
- Website
- Groome Transportation
Bus from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Birmingham-Shuttlesworth
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $40–65
- Website
- Groome Transportation
- Schedules at
- Groome Transportation
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tuscaloosa Bus Stop to Jackson
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Jackson to St Louis Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $90–140
- Website
- Greyhound
Bus from St Louis Bus Station to Kansas City Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Tuscaloosa Bus Stop to Jackson
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Champaign Intermodal Trans Ctr to Des Moines
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Tuscaloosa Bus Stop to Atlanta Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Website
- Greyhound
Bus from Tuscaloosa Bus Stop to Shreveport Bus Station
- Ave. Duration
- 8h 50m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Website
- Greyhound
Bus from Shreveport Bus Station to Texarkana
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $13–20
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Texarkana to Kansas City
- Ave. Duration
- 9h 5m
- Frequency
- Twice daily
- Estimated price
- $110–160
- Book at
- Jefferson Lines
- Adult
- $110–160
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 241+ hotels available in Des Moines.














