There are 10 ways to get from Tuscaloosa to Des Moines by car, plane, bus (Greyhound), bus, train, or bus (Greyhound, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Golden Triangle Regional Airport, fly
best- Drive from Tuscaloosa to Golden Triangle Regional Airport (GTR)car
- Fly from Golden Triangle Regional Airport (GTR) to Des Moines (DSM)plane GTR - DSM
6h 14m$180–789Drive 788.9 mi
cheapest- Drive from Tuscaloosa to Des Moinescar 788.9 mi
15h 7m$144–208Bus
- Take the bus from Tuscaloosa Bus Stop to Jacksonbus
- Take the bus from Jackson to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Des Moinesbus
23h 45m$174–345Bus, train
- Take the bus from Tuscaloosa Bus Stop to Jacksonbus
- Take the train from Jackson to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Des Moinesbus
25h 40m$279–575Bus to Birmingham–Shuttlesworth International Airport, fly
- Take the bus from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Birmingham-Shuttlesworthbus
- Fly from Birmingham–Shuttlesworth International Airport (BHM) to Des Moines (DSM)plane BHM - DSM
6h 31m$255–1,034Drive to Montgomery Regional Airport, fly
- Drive from Tuscaloosa to Montgomery-Airport-MGMcar
- Fly from Montgomery Regional Airport (MGM) to Des Moines (DSM)plane MGM - DSM
6h 29m$176–749Drive to Huntsville International Airport-Carl T Jones Field, fly
- Drive from Tuscaloosa to Huntsville International Airport-Carl T Jones Field (HSV)car
- Fly from Huntsville International Airport-Carl T Jones Field (HSV) to Des Moines (DSM)plane HSV - DSM
7h 2m$212–907Bus to Hartsfield-Jackson Atlanta International Airport, fly
- Take the bus from Tuscaloosa Bus Stop to Atlanta Bus Stationbus
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Des Moines (DSM)plane ATL - DSM
8h 30m$203–885Bus, train via Des Moines
- Take the bus from Tuscaloosa Bus Stop to Jacksonbus
- Take the train from Jackson to Champaign-Urbanatrain
- Take the bus from Champaign to Des Moinesbus
27h 50mBus via Atlanta
- Take the bus from Tuscaloosa Bus Stop to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Springfield SMTD Transfer Centerbus
- Take the bus from Springfield to Galesburg Amtrak Stationbus
- Take the bus from Galesburg to Des Moinesbus
30h 26m
Tuscaloosa to Des Moines by bus
Questions & Answers
The cheapest way to get from Tuscaloosa to Des Moines is to drive which costs $140 - $210 and takes 15h 7m.
The fastest way to get from Tuscaloosa to Des Moines is to drive and fly which takes 6h 14m and costs $180 - $800.
No, there is no direct bus from Tuscaloosa to Des Moines. However, there are services departing from Tuscaloosa Bus Stop and arriving at Des Moines via Jackson and St Louis Bus Station. The journey, including transfers, takes approximately 23h 45m.
The distance between Tuscaloosa and Des Moines is 704 miles. The road distance is 793.5 miles.
The best way to get from Tuscaloosa to Des Moines without a car is to bus which takes 23h 45m and costs $170 - $350.
It takes approximately 6h 14m to get from Tuscaloosa to Des Moines, including transfers.
Tuscaloosa to Des Moines bus services, operated by Greyhound-us, depart from Tuscaloosa Bus Stop station.
Tuscaloosa to Des Moines bus services, operated by Greyhound-us, arrive at Jackson station.
Yes, the driving distance between Tuscaloosa to Des Moines is 794 miles. It takes approximately 15h 7m to drive from Tuscaloosa to Des Moines.
Book your Tuscaloosa to Des Moines bus tickets online with Omio and FlixBus.
What companies run services between Tuscaloosa, AL, USA and Des Moines, IA, USA?
You can take a bus from Tuscaloosa Bus Stop to Des Moines via Jackson and St Louis Bus Station in around 23h 45m.
- Website
- aa.com
Flights from Golden Triangle Regional Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $170–800
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $190–950
Flights from Montgomery Regional Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $180–850
Flights from Montgomery Regional Airport to Des Moines via Reagan Washington
- Ave. Duration
- 5h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–950
Flights from Montgomery Regional Airport to Des Moines via Charlotte
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $180–800
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Charlotte
- Ave. Duration
- 6h 44m
- When
- Every day
- Estimated price
- $210–1,000
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $220–1,000
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 32m
- When
- Every day
- Estimated price
- $170–850
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $170–850
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 9m
- When
- Monday to Saturday
- Estimated price
- $190–900
- Website
- delta.com
Flights from Golden Triangle Regional Airport to Des Moines via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 7h 34m
- When
- Every day
- Estimated price
- $150–750
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $190–950
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Detroit
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Montgomery Regional Airport to Des Moines via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $140–700
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $180–900
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Detroit
- Ave. Duration
- 6h 53m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–950
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $150–800
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Detroit
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $210–950
- Website
- united.com
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $190–950
Flights from Montgomery Regional Airport to Des Moines via Houston
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $190–850
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $170–850
Flights from Huntsville International Airport-Carl T Jones Field to Des Moines via Houston
- Ave. Duration
- 7h 14m
- When
- Every day
- Estimated price
- $250–1,100
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $170–850
- Website
- southwest.com
Flights from Birmingham–Shuttlesworth International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 5h 17m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $190–950
Flights from Hartsfield-Jackson Atlanta International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 30m
- When
- Sunday, Saturday, Monday, Thursday, and Friday
- Estimated price
- $170–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jackson to Champaign-Urbana
- Ave. Duration
- 12h 45m
- Frequency
- Once daily
- Estimated price
- $200–410
- Website
- https://www.amtrak.com/home.html
Train from Jackson to Champaign-Urbana
- Ave. Duration
- 12h 45m
- Frequency
- Once daily
- Estimated price
- $200–410
- Website
- https://www.amtrak.com/home.html
- Website
- greyhound.com
Bus from Tuscaloosa Bus Stop to Jackson
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Jackson to St Louis Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Tuscaloosa Bus Stop to Jackson
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Tuscaloosa Bus Stop to Atlanta Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Schedules at
- greyhound.com
Bus from Tuscaloosa Bus Stop to Jackson
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Tuscaloosa Bus Stop to Atlanta Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Schedules at
- greyhound.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Tuscaloosa Bus Stop to Jackson
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
Bus from Jackson to St Louis Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $80–160
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Des Moines
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from Tuscaloosa Bus Stop to Jackson
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
Bus from Champaign Intermodal Trans Ctr to Des Moines
- Ave. Duration
- 7h 45m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
Bus from Tuscaloosa Bus Stop to Atlanta Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Tuscaloosa Bus Stop to Jackson
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
Bus from Tuscaloosa Bus Stop to Atlanta Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Phone
- +1 (205) 719-0469
- [email protected]
- Website
- groometransportation.com
Bus from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Birmingham-Shuttlesworth
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $40–65
- Website
- https://groometransportation.com
- Schedules at
- https://groometransportation.com/birmingham/
- Website
- example.com
Bus from Champaign to Des Moines
- Ave. Duration
- 9h 55m
- Frequency
- Once daily
- Schedules at
- example.com
Bus from Galesburg to Des Moines
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Schedules at
- example.com
- Website
- flixbus.com
Bus from Atlanta Bus Station to Springfield SMTD Transfer Center
- Ave. Duration
- 12h 50m
- Frequency
- Once daily
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Springfield to Galesburg Amtrak Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- https://www.amtrak.com/home.html
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 252+ hotels available in Des Moines.





