Rome2Rio

How to get fromTuscaloosa to St. Louisby bus, plane, bus (Greyhound), train, car, or bus (Greyhound, Flixbus, Amtrak)

Find Transport to St. Louis

See all options

There are 8 ways to get from Tuscaloosa to St. Louis by bus, plane, bus (Greyhound), train, car, or bus (Greyhound, Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Birmingham–Shuttlesworth International Airport, fly

    best
    1. Take the bus from Embassy Suites by Hilton Tuscaloosa Alabama Dowtown to Birmingham-Shuttlesworthbus bus
    2. Fly from Birmingham–Shuttlesworth International Airport (BHM) to Lambert–St. Louis International Airport (STL)plane plane BHM - STL
    6h 33m
    $141–616

  2. Drive  473.8 mi

    cheapest
    1. Drive from Tuscaloosa to St. Louiscar car 473.8 mi
    8h 48m
    $87–125

  3. Bus (Greyhound)

    1. Take the bus from Tuscaloosa Bus Stop to Jacksonbus bus Greyhound US0604
    2. Take the bus from Jackson to St Louis Bus Stationbus bus Greyhound US1173
    14h 35m
    $110–176

  4. Bus, train

    1. Take the bus from Tuscaloosa Bus Stop to Jacksonbus bus
    2. Take the train from Jackson to Carbondaletrain train
    3. Take the bus from Carbondale to St. Louisbus bus
    17h 3m
    $144–351

  5. Drive to Golden Triangle Regional Airport, fly

    1. Drive from Tuscaloosa to Golden Triangle Regional Airport (GTR)car car
    2. Fly from Golden Triangle Regional Airport (GTR) to Lambert–St. Louis International Airport (STL)plane plane GTR - STL
    6h 51m
    $116–571

  6. Drive to Montgomery Regional Airport, fly

    1. Drive from Tuscaloosa to Montgomery-Airport-MGMcar car
    2. Fly from Montgomery Regional Airport (MGM) to Lambert–St. Louis International Airport (STL)plane plane MGM - STL
    7h 36m
    $112–581

  7. Bus to Hartsfield-Jackson Atlanta International Airport, fly

    1. Take the bus from Tuscaloosa Bus Stop to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Lambert–St. Louis International Airport (STL)plane plane ATL - STL
    8h 28m
    $129–607

  8. Bus via Atlanta

    1. Take the bus from Tuscaloosa Bus Stop to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale to St. Louisbus bus
    17h 11m
    $112–196

Tuscaloosa to St. Louis by bus (Greyhound)

Calendar7Weekly Buses
Duration14h 35mAverage Duration
Ticket$110Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Tuscaloosa to St. Louis.ExpandLaunch map view
  • Distance: 487.7 mi
  • Duration: 6h 33m

What companies run services between Tuscaloosa, AL, USA and St. Louis, MO, USA?

You can take a bus from Tuscaloosa Bus Stop to St Louis Bus Station via Jackson in around 14h 35m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There