Rome2Rio

How to get fromTuscany to Iserniaby train (Trenitalia), bus, car, plane, or train

Find Transport to Isernia

See all options

There are 6 ways to get from Tuscany to Isernia by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Firenze Santa Maria Novella to Roma Tiburtinatrain train 8902 / ...
    2. Take the train from Roma Tiburtina to Iserniatrain train Re
    4h 40m
    €55–103

  2. Bus

    cheapest
    1. Take the bus from Florence to Roma, Autostazione Tiburtinabus bus N520 / ...
    2. Take the bus from Roma, Autostazione Tiburtina to Iserniabus bus Rome Tiburtina
    6h 35m
    €22–61

  3. Drive 428.2 km

    1. Drive from Florence to Iserniacar car 428.2 km
    4h 6m
    €67–97

  4. Fly, train

    1. Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane plane FLR - FCO
    2. Take the train from Roma Termini to Iserniatrain train
    6h 1m
    €88–229

  5. Train via Rome (Trenitalia)

    1. Take the train from Firenze S.M.N. to Roma Terminitrain train Fr
    2. Take the train from Roma Termini to Iserniatrain train Re
    4h 52m
    €51–115

  6. Bus, train

    1. Take the bus from Florence to Cassino Bar Varlesebus bus
    2. Take the train from Cassino to Iserniatrain train Re
    7h 21m
    €33–48

Tuscany to Isernia by bus

Calendar14Weekly Buses
Duration6h 35mAverage Duration
Ticket€22Cheapest Price
See schedules

Questions & Answers

Map of how to get from Tuscany to Isernia.ExpandLaunch map view
  • Distance: 441.4 km
  • Duration: 4h 40m

What companies run services between Tuscany, Italy and Isernia, Italy?

You can take a train from Firenze Santa Maria Novella to Isernia via Roma Tiburtina in around 4h 40m. Alternatively, you can take a bus from Florence to Isernia via Roma, Autostazione Tiburtina in around 6h 35m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

More Questions & Answers