Rome2Rio

How to get fromTuscany to Sicilyby plane, train, ferry, car, car ferry, bus, or train (Trenitalia)

Find Transport to Sicily

See all options
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

There are 10 ways to get from Tuscany to Sicily by plane, train, ferry, car, car ferry, bus, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Pisa International Airport to Palermo Airport

    best
    1. Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane plane PSA - PMO
    2h 14m
    €40–218

  2. Fly Florence Peretola Airport to Catania–Fontanarossa Airport

    cheapest
    1. Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane plane FLR - CTA
    3h 15m
    €27–166

  3. Train, ferry

    1. Take the train from Firenze S.M.N. to Napoli Afragolatrain train Fr
    2. Take the train from Napoli Afragola to Villa S.Giovannitrain train Fr
    3. Take the ferry from Villa S.Giovanni to Messina Marittimaferry ferry V1 / ...
    4. Take the train from Messina Centrale to Palermo Centraletrain train Re
    12h 32m

  4. Drive, car ferry

    1. Drive from Florence to Civitavecchia Portcar car
    2. Take the carferry from Civitavecchia Port to Palermo Portocarferry car ferry
    16h 36m
    €105–151

  5. Bus via Siena

    1. Take the bus from Firenze Autostazione to P.Camolliabus bus 131R / ...
    2. Take the bus from Siena to Palermobus bus N597
    18h 49m
    €107–168

  6. Fly Pisa International Airport to Catania–Fontanarossa Airport

    1. Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane plane PSA - CTA
    1h 57m
    €43–191

  7. Fly Florence Peretola Airport to Palermo Airport

    1. Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane plane FLR - PMO
    3h 37m
    €35–207

  8. Train

    1. Take the train from Firenze Santa Maria Novella to Roma Terminitrain train 8111 / ...
    2. Take the train from Roma Termini to Palermo Centraletrain train Ic
    14h 37m
    €126–221

  9. Train via Firenze S.M.N.

    1. Take the train from Firenze S.M.N. to Roma Terminitrain train Fr
    2. Take the train from Roma Termini to Palermo Centraletrain train Ic
    14h 43m
    €125–232

  10. Bus

    1. Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus bus
    21h 37m
    €194–274

Pisa International Airport (PSA) to Palermo Airport (PMO) flights

Calendar23Weekly Planes
Duration1h 29mAverage Duration
Ticket€21Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Tuscany to Sicily.ExpandLaunch map view
  • Distance: 684.5 km
  • Duration: 2h 14m

What companies run services between Tuscany, Italy and Sicily, Italy?

Ulendo Airlink and Ryanair fly from Pisa International Airport (PSA) to Palermo Airport (PMO) 3 times a day. Alternatively, you can take a bus from Firenze Autostazione to Piazza Boiardo via P.Camollia, Siena, Palermo, and Stazione Centrale Pensilina Esterna in around 18h 49m.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

Booking & Getting There