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How to get fromTuscany to Sicilyby plane, train, ferry, car, car ferry, bus, or train (Trenitalia)

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There are 11 ways to get from Tuscany to Sicily by plane, train, ferry, car, car ferry, bus, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Pisa International Airport to Palermo Airport

    best
    1. Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane plane PSA - PMO
    2h 13m
    €34–194

  2. Train, ferry

    1. Take the train from Firenze Santa Maria Novella to Napoli Afragolatrain train
    2. Take the train from Napoli Afragola to Villa S.Giovannitrain train Fr
    3. Take the ferry from Villa S.Giovanni to Messina Marittimaferry ferry V1 / ...
    4. Take the train from Messina Centrale to Palermo Centraletrain train Re
    12h 29m

  3. Drive, car ferry

    1. Drive from Florence to Civitavecchia Portcar car
    2. Take the car ferry from Civitavecchia Port to Palermo Portocarferry car ferry
    16h 36m
    €100–147

  4. Bus

    1. Take the bus from Florence Villa Constanza Bus Station to Palermobus bus N597 / ...
    18h 53m
    €103–184

  5. Fly Pisa International Airport to Catania–Fontanarossa Airport

    1. Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane plane PSA - CTA
    1h 57m
    €43–152

  6. Fly Florence Peretola Airport to Catania–Fontanarossa Airport

    1. Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane plane FLR - CTA
    3h 15m
    €46–176

  7. Fly Pisa International Airport to Vincenzo Magliocco Airport

    1. Fly from Pisa International Airport (PSA) to Vincenzo Magliocco Airport (CIY)plane plane PSA - CIY
    1h 55m
    €96–270

  8. Fly Pisa International Airport to Trapani Airport

    1. Fly from Pisa International Airport (PSA) to Trapani Airport (TPS)plane plane PSA - TPS
    2h 55m
    €40–131

  9. Train (Trenitalia)

    1. Take the train from Firenze S.M.N. to Roma Terminitrain train Fr
    2. Take the train from Roma Termini to Palermo Centraletrain train Ic
    14h 46m
    €119–267

  10. Train #2

    1. Take the train from Firenze Santa Maria Novella to Roma Terminitrain train 8111 / ...
    2. Take the train from Roma Termini to Palermo Centraletrain train Ic
    14h 46m
    €124–256

  11. Bus via Palermo Piazza Cairoli

    1. Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus bus
    21h 43m

Tuscany to Sicily by bus

Calendar14Weekly Buses
Duration18h 53mAverage Duration
Ticket€103Cheapest Price
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Questions & Answers

Map of how to get from Tuscany to Sicily.ExpandLaunch map view
  • Distance: 684.5 km
  • Duration: 2h 13m

What companies run services between Tuscany, Italy and Sicily, Italy?

Ryanair flies from Pisa International Airport (PSA) to Palermo Airport (PMO) 3 times a day. Alternatively, FlixBus operates a bus from Florence Villa Constanza Bus Station to Palermo twice daily. Tickets cost €100–180 and the journey takes 17h.

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