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How to get fromTuscany to Sicilyby plane, train, ferry, car, car ferry, bus, or train (Trenitalia)

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There are 9 ways to get from Tuscany to Sicily by plane, train, ferry, car, car ferry, bus, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Pisa International Airport to Palermo Airport

    best
    1. Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane plane PSA - PMO
    2h 13m
    €39–224

  2. Fly Florence Peretola Airport to Catania–Fontanarossa Airport

    cheapest
    1. Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane plane FLR - CTA
    3h 15m
    €32–186

  3. Train, ferry

    1. Take the train from Firenze S.M.N. to Napoli Afragolatrain train Fr
    2. Take the train from Napoli Afragola to Villa S.Giovannitrain train Fr
    3. Take the ferry from Villa S.Giovanni to Messina Marittimaferry ferry V1 / ...
    4. Take the train from Messina Centrale to Palermo Centraletrain train Re
    12h 35m

  4. Drive, car ferry

    1. Drive from Florence to Civitavecchia Portcar car
    2. Take the carferry from Civitavecchia Port to Palermo Portocarferry car ferry
    16h 36m
    €100–143

  5. Bus via Siena

    1. Take the bus from Firenze Autostazione to P.Camolliabus bus 131R / ...
    2. Take the bus from Siena to Palermobus bus N597
    18h 53m
    €102–168

  6. Fly Pisa International Airport to Catania–Fontanarossa Airport

    1. Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane plane PSA - CTA
    1h 57m
    €43–196

  7. Fly Pisa International Airport to Trapani Airport

    1. Fly from Pisa International Airport (PSA) to Trapani Airport (TPS)plane plane PSA - TPS
    2h 55m
    €45–289

  8. Train (Trenitalia)

    1. Take the train from Firenze S.M.N. to Roma Terminitrain train Fr
    2. Take the train from Roma Termini to Palermo Centraletrain train Ic
    14h 34m
    €119–247

  9. Bus

    1. Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus bus
    21h 41m
    €194–274

Pisa International Airport (PSA) to Palermo Airport (PMO) flights

Calendar21Weekly Planes
Duration1h 20mAverage Duration
Ticket€35Cheapest Price
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Questions & Answers

Map of how to get from Tuscany to Sicily.ExpandLaunch map view
  • Distance: 684.5 km
  • Duration: 2h 13m

What companies run services between Tuscany, Italy and Sicily, Italy?

Ryanair flies from Pisa International Airport (PSA) to Palermo Airport (PMO) 3 times a day. Alternatively, you can take a bus from Firenze Autostazione to Piazza Boiardo via P.Camollia, Siena, Palermo, and Stazione Centrale Pensilina Esterna in around 18h 53m.

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