There are 5 ways to get from Tustin to San Luis Obispo by bus (Greyhound, Flixbus), train (Amtrak), car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Santa Ana to Los Angeles Union Stationbus Tijuana
- Take the bus from Los Angeles Union Station to San Luis Obispo Railroad Museumbus FlixBus 2005
6h$40–68Train (Amtrak)
- Take the train from Santa Ana to San Luis Obispotrain Pacific Surfliner
6h 33m$80–170Drive 219 mi
- Drive from Tustin to San Luis Obispocar 219 mi
4h 3m$40–58Train to Los Angeles International Airport, fly
- Take the train from Santa Ana to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to San Luis Obispo County Regional Airport (SBP)plane LAX - SBP
4h 59m$239–478Train to San Diego International Airport, fly
- Take the train from Santa Ana to San Diego Old Town Transportation Centertrain
- Fly from San Diego International Airport (SAN) to San Luis Obispo County Regional Airport (SBP)plane SAN - SBP
5h 33m$200–410
Tustin to San Luis Obispo by bus
Questions & Answers
The cheapest way to get from Tustin to San Luis Obispo is to bus which costs $40 - $70 and takes 6h.
The fastest way to get from Tustin to San Luis Obispo is to drive which takes 4h 3m and costs $40 - $60.
No, there is no direct bus from Tustin to San Luis Obispo. However, there are services departing from Santa Ana and arriving at San Luis Obispo Railroad Museum via Los Angeles Union Station. The journey, including transfers, takes approximately 6h.
Yes, there is a direct train departing from Santa Ana and arriving at San Luis Obispo. Services depart twice daily, and operate every day. The journey takes approximately 6h 33m.
The distance between Tustin and San Luis Obispo is 226 miles. The road distance is 220.3 miles.
The best way to get from Tustin to San Luis Obispo without a car is to bus which takes 6h and costs $40 - $70.
It takes approximately 6h to get from Tustin to San Luis Obispo, including transfers.
Tustin to San Luis Obispo bus services, operated by Greyhound Mexico, depart from Santa Ana station.
Tustin to San Luis Obispo train services, operated by Amtrak, depart from Santa Ana station.
The best way to get from Tustin to San Luis Obispo is to bus which takes 6h and costs $40 - $70. Alternatively, you can train, which costs $80 - $170 and takes 6h 33m.
What companies run services between Tustin, CA, USA and San Luis Obispo, CA, USA?
You can take a bus from Santa Ana to San Luis Obispo Railroad Museum via Los Angeles Union Station in around 6h. Alternatively, Amtrak operates a train from Santa Ana to San Luis Obispo twice daily. Tickets cost $80–170 and the journey takes 6h 33m.
- Website
- united.com
Flights from Los Angeles International Airport to San Luis Obispo County Regional Airport
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $25–180
Flights from San Diego International Airport to San Luis Obispo County Regional Airport via Los Angeles International Airport
- Ave. Duration
- 2h 58m
- When
- Wednesday
- Estimated price
- $30–200
- Website
- alaskaair.com
Flights from San Diego International Airport to San Luis Obispo County Regional Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $170–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Santa Ana to San Luis Obispo
- Ave. Duration
- 6h 33m
- Frequency
- Twice daily
- Estimated price
- $80–170
- Website
- https://www.amtrak.com/home.html
Train from Santa Ana to Los Angeles
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $11–23
- Website
- https://www.amtrak.com/home.html
Train from Santa Ana to San Diego Old Town Transportation Center
- Ave. Duration
- 1h 51m
- Frequency
- Hourly
- Estimated price
- $28–60
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-800-231-2222
- [email protected]
- Website
- greyhound.com.mx
Bus from Santa Ana to Los Angeles Union Station
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $10–14
- Schedules at
- greyhound.com.mx
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Los Angeles Union Station to San Luis Obispo Railroad Museum
- Ave. Duration
- 4h
- Frequency
- 4 times a week
- Estimated price
- $30–55
- Schedules at
- flixbus.com
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More Questions & Answers
Tustin to San Luis Obispo bus services, operated by Greyhound Mexico, arrive at Los Angeles Union Station.
Tustin to San Luis Obispo train services, operated by Amtrak, arrive at San Luis Obispo station.
Yes, the driving distance between Tustin to San Luis Obispo is 220 miles. It takes approximately 4h 3m to drive from Tustin to San Luis Obispo.
Book your Tustin to San Luis Obispo train tickets online with Omio.
Book your Tustin to San Luis Obispo bus tickets online with Omio.
There are 287+ hotels available in San Luis Obispo.












