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How to get fromTwinsburg to Buffaloby train (Amtrak), bus, car, tram, plane, or bus (Greyhound)

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There are 5 ways to get from Twinsburg to Buffalo by train (Amtrak), bus, car, tram, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Cleveland Amtrak to Buffalo Depew Stationtrain train Lake Shore Limited
    5h 2m
    $163–372

  2. Bus

    cheapest
    1. Take the bus from Akron to Buffalobus bus Bsb 10
    6h 17m
    $22–66

  3. Drive  192.6 mi

    1. Drive from Twinsburg to Buffalocar car 192.6 mi
    3h 35m
    $33–48

  4. Line 32 bus, bus, tram, fly

    1. Take the bus from E. Aurora Rd @ Grande Village to Southgate Transit Centerbus bus
    2. Take the bus from Southgate Transit Center Stop #4 to Van Aken-Warrensville Sta Stop 2bus bus
    3. Take the tram from Van Aken & Warrensville Stn to E 55Th St Stationtram tram
    4. Fly from Cleveland-Hopkins International Airport (CLE) to Buffalo Niagara International Airport (BUF)plane plane CLE - BUF
    7h 59m

  5. Bus via Brook Park (Greyhound)

    1. Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland Bus Stationbus bus Greyhound US0164
    2. Take the bus from Cleveland Bus Station to Buffalobus bus Greyhound US0171 / ...
    7h 17m
    $42–66

Twinsburg to Buffalo by bus

Calendar7Weekly Buses
Duration6h 17mAverage Duration
Ticket$22Cheapest Price
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Comparing Your Travel Options

Map of how to get from Twinsburg to Buffalo.ExpandLaunch map view
  • Distance: 215.7 mi
  • Duration: 5h 2m

What companies run services between Twinsburg, OH, USA and Buffalo, NY, USA?

Amtrak operates a train from Cleveland Amtrak to Buffalo Depew Station twice daily. Tickets cost $100–160 and the journey takes 3h 3m. Alternatively, Barons Bus operates a bus from Akron to Buffalo once daily. Tickets cost $21–65 and the journey takes 4h 15m.

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