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How to get fromTwinsburg to Chicagoby train (Amtrak), bus (Flixbus, Greyhound), car, bus, plane, or bus (Greyhound, Flixbus, Amtrak)

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There are 9 ways to get from Twinsburg to Chicago by train (Amtrak), bus (Flixbus, Greyhound), car, bus, plane, or bus (Greyhound, Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train Floridian / ...
    7h 24m
    $171–302

  2. Line 104 bus to Akron, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from E. Aurora Rd @ Grande Village to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Chicago O'Hare International Airport (ORD)plane plane CAK - ORD
    5h 42m
    $43–266

  3. Bus

    1. Take the bus from Robert K Pfaff Transit Center - Akron to Chicago Bus Stationbus bus FlixBus N2641
    9h 36m
    $91–131

  4. Drive 356.7 mi

    1. Drive from Twinsburg to Chicagocar car 356.7 mi
    6h 2m
    $66–94

  5. Bus via Toledo

    1. Take the bus from Robert K Pfaff Transit Center - Akron to Toledo Bus Stopbus bus Greyhound US0164
    2. Take the bus from Toledo to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    11h 9m
    $126–181

  6. Line 104 bus, bus to Cleveland-Hopkins International Airport, fly to Chicago Midway International Airport

    1. Take the bus from E. Aurora Rd @ Grande Village to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland Bus Stationbus bus
    3. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW)plane plane CLE - MDW
    5h 42m
    $71–390

  7. Line 104 bus, bus to Cleveland-Hopkins International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from E. Aurora Rd @ Grande Village to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland Bus Stationbus bus
    3. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago O'Hare International Airport (ORD)plane plane CLE - ORD
    6h 7m
    $381–820

  8. Line 104 bus, bus, bus to Pittsburgh International Airport, fly to Chicago Midway International Airport

    1. Take the bus from E. Aurora Rd @ Grande Village to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Pittsburgh Intermodal Stationbus bus
    3. Take the bus from Liberty Ave + Tito Way to Pittsburgh International Airportbus bus
    4. Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane plane PIT - MDW
    8h 18m

  9. Line 104 bus, bus, bus to Pittsburgh International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from E. Aurora Rd @ Grande Village to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Pittsburgh Intermodal Stationbus bus
    3. Take the bus from Liberty Ave + Tito Way to Pittsburgh International Airportbus bus
    4. Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane plane PIT - ORD
    8h 45m

Akron (CAK) to Chicago O'Hare International Airport (ORD) flights

Calendar41Weekly Planes
Duration1h 51mAverage Duration
Ticket$42Cheapest Price
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Questions & Answers

Map of how to get from Twinsburg to Chicago.ExpandLaunch map view
  • Distance: 360.4 mi
  • Duration: 7h 24m

What companies run services between Twinsburg, OH, USA and Chicago, IL, USA?

Amtrak operates a train from Cleveland Amtrak to Chicago Union Station 3 times a day. Tickets cost $110–230 and the journey takes 6h 46m. Alternatively, Flixbus USA operates a bus from Robert K Pfaff Transit Center - Akron to Chicago Bus Station 6 times a week. Tickets cost $60–110 and the journey takes 7h 50m. Two other operators also service this route.

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