There are 7 ways to get from Twinsburg to Chicago by train (Amtrak), bus, car, plane, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Cleveland Amtrak to Chicago Union Stationtrain Floridian / ...
7h 24m$146–272Line 104 bus to Akron, fly to Chicago O'Hare International Airport
cheapest- Take the bus from E. Aurora Rd @ Grande Village to Robert K Pfaff Transit Center - Akronbus
- Fly from Akron (CAK) to Chicago O'Hare International Airport (ORD)plane CAK - ORD
5h 32m$38–236Bus via Cleveland
- Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland, OHbus Cinncinati,OH-Buffalo / ...
- Take the bus from Cleveland to Chicagobus Cleveland / ...
11h 7m$39–121Drive 356.7 mi
- Drive from Twinsburg to Chicagocar 356.7 mi
6h 2m$66–94Bus
- Take the bus from Robert K Pfaff Transit Center - Akron to Chicago Bus Stationbus Greyhound US0164
11h 41m$56–96Line 104 bus, bus to Cleveland-Hopkins International Airport, fly to Chicago Midway International Airport
- Take the bus from E. Aurora Rd @ Grande Village to Robert K Pfaff Transit Center - Akronbus
- Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland Bus Stationbus
- Fly from Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW)plane CLE - MDW
5h 42m$66–408Line 104 bus, bus to Cleveland-Hopkins International Airport, fly to Chicago O'Hare International Airport
- Take the bus from E. Aurora Rd @ Grande Village to Robert K Pfaff Transit Center - Akronbus
- Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland Bus Stationbus
- Fly from Cleveland-Hopkins International Airport (CLE) to Chicago O'Hare International Airport (ORD)plane CLE - ORD
6h 6m$371–818
Akron (CAK) to Chicago O'Hare International Airport (ORD) flights
Comparing Your Travel Options
The cheapest way to get from Twinsburg to Chicago is to bus which costs $55 - $100 and takes 11h 41m.
The fastest way to get from Twinsburg to Chicago is to line 104 bus and fly which takes 5h 32m and costs $35 - $240.
No, there is no direct bus from Twinsburg to Chicago. However, there are services departing from Darrow Rd @ Giant Eagle and arriving at Chicago via Robert K Pfaff Transit Center - Akron and Cleveland. The journey, including transfers, takes approximately 11h 7m.
No, there is no direct train from Twinsburg to Chicago station. However, there are services departing from Cleveland Amtrak and arriving at Chicago Union Station via . The journey, including transfers, takes approximately 7h 24m.
The distance between Twinsburg and Chicago is 362 miles. The road distance is 358.7 miles.
The best way to get from Twinsburg to Chicago without a car is to train which takes 7h 24m and costs $140 - $280.
It takes approximately 7h 24m to get from Twinsburg to Chicago, including transfers.
Twinsburg to Chicago bus services, operated by Barons Bus, depart from Robert K Pfaff Transit Center - Akron station.
Twinsburg to Chicago train services, operated by Amtrak, depart from Cleveland Amtrak station.
The best way to get from Twinsburg to Chicago is to train which takes 7h 24m and costs $140 - $280. Alternatively, you can bus via Cleveland, which costs $35 - $130 and takes 11h 7m.
What companies run services between Twinsburg, OH, USA and Chicago, IL, USA?
Amtrak operates a train from Cleveland Amtrak to Chicago Union Station 3 times a day. Tickets cost $85–200 and the journey takes 6h 46m. Alternatively, you can take a bus from Darrow Rd @ Giant Eagle to Chicago via Robert K Pfaff Transit Center - Akron and Cleveland in around 11h 7m.
- Website
- united.com
Flights from Akron to Chicago O'Hare International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $35–230
Flights from Cleveland-Hopkins International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $45–310
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Cleveland Amtrak to Chicago Union Station
- Ave. Duration
- 6h 46m
- Frequency
- 3 times a day
- Estimated price
- $85–200
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Robert K Pfaff Transit Center - Akron to Cleveland, OH
- Ave. Duration
- 45 min
- Frequency
- 3 times a day
- Estimated price
- $3–35
- Website
- Barons Bus
Bus from Cleveland to Chicago
- Ave. Duration
- 7h 35m
- Frequency
- Twice daily
- Estimated price
- $35–85
- Website
- Barons Bus
Want to know more about travelling around United States
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Booking & Getting There
Twinsburg to Chicago bus services, operated by Barons Bus, arrive at Cleveland, OH station.
Chicago is 1h behind Twinsburg. It is currently 8:39 AM in Twinsburg and 7:39 AM in Chicago.
Twinsburg to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Twinsburg to Chicago is 359 miles. It takes approximately 6h 2m to drive from Twinsburg to Chicago.
There are 1280+ hotels available in Chicago.