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How to get fromTyler to Knoxvilleby plane, bus, shuttle, or car

Find Transport to Knoxville

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There are 7 ways to get from Tyler to Knoxville by plane, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Tyler

    best
    1. Fly from Tyler (TYR) to Mcghee Tyson Airport (TYS)plane plane TYR - TYS
    5h 12m
    $253–1,041

  2. Drive  779 mi

    cheapest
    1. Drive from Tyler to Knoxvillecar car 779 mi
    13h 16m
    $143–206

  3. Bus, shuttle, drive

    1. Take the bus from Tyler to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Boonebus bus
    4. Take a shuttle bus from Boone to Black Bear Resortshuttle bus
    5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    6. Drive from Hot Springs to Knoxvillecar car
    30h 49m
    $399–501

  4. Bus to Dallas, fly

    1. Take the bus from Tyler to Dallas Bus Stationbus bus
    2. Fly from Dallas (DAL) to Mcghee Tyson Airport (TYS)plane plane DAL - TYS
    5h 43m
    $237–1,002

  5. Bus to Gregg County Airport, fly

    1. Take the bus from Tyler to Longview Bus Stationbus bus
    2. Fly from Gregg County Airport (GGG) to Mcghee Tyson Airport (TYS)plane plane GGG - TYS
    8h 45m
    $259–1,101

  6. Bus to Shreveport, fly

    1. Take the bus from Tyler to Shreveport Bus Stationbus bus
    2. Fly from Shreveport (SHV) to Mcghee Tyson Airport (TYS)plane plane SHV - TYS
    8h 23m
    $221–994

  7. Bus to Dallas/Fort Worth International Airport, fly

    1. Take the bus from Tyler to Dallas Bus Stationbus bus
    2. Fly from Dallas/Fort Worth International Airport (DFW) to Mcghee Tyson Airport (TYS)plane plane DFW - TYS
    6h 33m
    $224–949

Tyler (TYR) to Mcghee Tyson Airport (TYS) flights

Calendar35Weekly Planes
Duration5h 59mAverage Duration
Ticket$182Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Tyler to Knoxville.ExpandLaunch map view
  • Distance: 715.6 mi
  • Duration: 5h 12m

What companies run services between Tyler, TX, USA and Knoxville, TN, USA?

American Airlines flies from Tyler (TYR) to Mcghee Tyson Airport (TYS) 5 times a day.

Airlines
Bus operators

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