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How to get fromTyrone to St. Louisby bus, plane, train, train (Amtrak), or car

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There are 5 ways to get from Tyrone to St. Louis by bus, plane, train, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Penn State University Park Airport, fly

    best
    1. Take the bus from Tyrone Bus Stop to State College Bus Stationbus bus
    2. Fly from Penn State University Park Airport (SCE) to Lambert–St. Louis International Airport (STL)plane plane SCE - STL
    7h 50m
    $119–614

  2. Train, bus

    1. Take the train from Tyrone Station to Pittsburgh Amtrak Stationtrain train Pennsylvanian
    2. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    17h 9m
    $131–264

  3. Train (Amtrak)

    1. Take the train from Tyrone Station to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    19h 46m
    $281–594

  4. Drive 707.1 mi

    1. Drive from Tyrone to St. Louiscar car 707.1 mi
    12h 20m
    $129–187

  5. Train to Pittsburgh International Airport, fly

    1. Take the train from Tyrone Station to Pittsburgh Amtrak Stationtrain train
    2. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    8h 13m
    $144–687

Tyrone to St. Louis by train and bus

Calendar7Weekly Services
Duration17h 9mAverage Duration
Ticket$131Cheapest Price
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Questions & Answers

Map of how to get from Tyrone to St. Louis.ExpandLaunch map view
  • Distance: 725.4 mi
  • Duration: 7h 50m

What companies run services between Tyrone, PA, USA and St. Louis, MO, USA?

You can take a train from Tyrone Station to St. Louis via Pittsburgh Amtrak Station and Chicago Union Station in around 19h 46m.

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