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How to get fromUNION STATION station to Santa Fe Depotby plane, bus (Greyhound, Amtrak), train (Amtrak), car, train, or bus

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There are 5 ways to get from UNION STATION station to Santa Fe Depot by plane, bus (Greyhound, Amtrak), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN)plane plane STL - SAN
    5h 44m
    $134–198

  2. Bus

    1. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus Greyhound US1210
    2. Take the bus from Los Angeles to San Diegobus bus Amtrak Thruway Connecting Service
    42h 55m
    $343–637

  3. Train (Amtrak)

    1. Take the train from St. Louis to Kansas Citytrain train
    2. Take the train from Kansas City to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    44h 59m
    $671–1,452

  4. Drive 1,797.9 mi

    1. Drive from UNION STATION station to Santa Fe Depotcar car 1,797.9 mi
    29h 11m
    $329–474

  5. Train, bus

    1. Take the train from St. Louis to Yuma Amtraktrain train
    2. Take the bus from 3rd Street @ Gila Street to William Brook Ave @ B Streetbus bus 95
    3. Take the bus from San Luis Río Colorado to Tijuanabus bus
    2d 15h
    $748–1,521

UNION STATION station to Santa Fe Depot by foot and bus

Calendar7Weekly Services
Duration42h 55mAverage Duration
Ticket$343Cheapest Price
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Questions & Answers

Map of how to get from UNION STATION station to Santa Fe Depot.ExpandLaunch map view
  • Distance: 1,573.5 mi
  • Duration: 5h 44m

What companies run services between UNION STATION station, MO, USA and Santa Fe Depot, San Diego County, CA, USA?

Southwest Airlines and American Airlines fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN) 5 times a day. Alternatively, you can take a vehicle from UNION STATION station to San Diego via St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 42h 55m.

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