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How to get fromUNION STATION station to Santa Fe Depotby plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

Find Transport to Santa Fe Depot

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There are 5 ways to get from UNION STATION station to Santa Fe Depot by plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN)plane plane STL - SAN
    5h 55m
    $134–248

  2. Train (Amtrak)

    1. Take the train from St. Louis to Kansas Citytrain train
    2. Take the train from Kansas City to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    44h 59m
    $524–1,322

  3. Bus

    1. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus Greyhound US1210
    2. Take the bus from Los Angeles Downtown to San Diegobus bus FlixBus 2017
    45h 14m
    $319–501

  4. Drive  1,797.9 mi

    1. Drive from UNION STATION station to Santa Fe Depotcar car 1,797.9 mi
    29h 11m
    $329–474

  5. Train, bus

    1. Take the train from St. Louis to Yuma Amtraktrain train
    2. Take the bus from 3rd Street @ Gila Street to William Brook Ave @ B Streetbus bus 95
    3. Take the bus from San Luis Río Colorado to Tijuanabus bus
    2d 15h
    $581–1,384

UNION STATION station to Santa Fe Depot by foot and train (Amtrak)

Calendar7Weekly Services
Duration44h 59mAverage Duration
Ticket$524Cheapest Price
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Comparing Your Travel Options

Map of how to get from UNION STATION station to Santa Fe Depot.ExpandLaunch map view
  • Distance: 1,573.5 mi
  • Duration: 5h 55m

What companies run services between UNION STATION station, MO, USA and Santa Fe Depot, San Diego County, CA, USA?

Southwest Airlines and United Airlines fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a vehicle from UNION STATION station to San Diego via St. Louis, Kansas City, and Fullerton Amtrak Station in around 44h 59m.

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Need to know: Greyhound

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