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How to get fromUW La Crosse to Chicagoby plane, train (Amtrak), bus (Greyhound, Flixbus), car, or bus

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There are 5 ways to get from UW La Crosse to Chicago by plane, train (Amtrak), bus (Greyhound, Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane plane LSE - ORD
    2h 20m
    $49–255
  2. Train (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    5h 12m
    $97–198
  3. Bus

    1. Take the bus from University of Wisconsin - La Crosse to Wisconsin Dellsbus bus Minneapolis
    2. Take the bus from Wisconsin Dells to Chicago Bus Stationbus bus Greyhound US0150
    6h 50m
    $61–108
  4. Drive 280.1 mi

    1. Drive from UW La Crosse to Chicagocar car 280.1 mi
    4h 37m
    $52–74
  5. Bus via Madison

    1. Take the bus from University of Wisconsin - La Crosse to UW-Madisonbus bus Minneapolis / ...
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus Van Galder
    7h 26m
    $68–118

UW La Crosse to Chicago by bus

Calendar14Weekly Buses
Duration6h 50mAverage Duration
Ticket$61Cheapest Price
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Questions & Answers

What companies run services between UW La Crosse, WI, USA and Chicago, IL, USA?

American Airlines and United Airlines fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD) 4 times a day. Alternatively, Amtrak operates a train from La Crosse Amtrak Station to Chicago Union Station 3 times a day. Tickets cost $90–190 and the journey takes 5h 8m.

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