There are 5 ways to get from University at Buffalo to Boston by plane, train, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, train
best- Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane BUF - LGA
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
6h 55m$225–714Drive 449.4 mi
cheapest- Drive from University at Buffalo to Bostoncar 449.4 mi
7h 52m$77–111Train (Amtrak)
- Take the train from Buffalo Depew Station to Bostontrain Lake Shore Limited
11h 40m$303–459Bus (Greyhound)
- Take the bus from Buffalo to Bostonbus Greyhound US0171
12h 31m$89–134Bus via Ithaca (Flixbus)
- Take the bus from Buffalo to Ithacabus FlixBus 2685 / ...
- Take the bus from Ithaca to Bostonbus FlixBus 2691
15h 6m$90–134
University at Buffalo to Boston by foot and bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from University at Buffalo to Boston is to drive which costs $75 - $120 and takes 7h 52m.
The fastest way to get from University at Buffalo to Boston is to fly and train which takes 6h 55m and costs $220 - $750.
No, there is no direct bus from University at Buffalo to Boston. However, there are services departing from Flint Circle and arriving at Boston via Main Street & University Station and Buffalo. The journey, including transfers, takes approximately 12h 31m.
No, there is no direct train from University at Buffalo station to Boston. However, there are services departing from Buffalo Depew Station and arriving at Boston via . The journey, including transfers, takes approximately 11h 40m.
The distance between University at Buffalo and Boston is 544 miles. The road distance is 452 miles.
The best way to get from University at Buffalo to Boston without a car is to train which takes 11h 40m and costs $300 - $460.
It takes approximately 6h 55m to get from University at Buffalo to Boston, including transfers.
University at Buffalo to Boston bus services, operated by Greyhound USA, depart from Buffalo station.
University at Buffalo to Boston train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from University at Buffalo to Boston is to train which takes 11h 40m and costs $300 - $460. Alternatively, you can bus, which costs $85 - $140 and takes 12h 31m.
What companies run services between University at Buffalo, NY, USA and Boston, MA, USA?
Amtrak operates a train from Buffalo Depew Station to Boston once daily. Tickets cost $270–420 and the journey takes 11h 27m. Alternatively, Greyhound USA operates a bus from Buffalo to Boston twice daily. Tickets cost $85–130 and the journey takes 10h 5m.
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $70–470
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $70–470
- Website
- united.com
Flights from Buffalo Niagara International Airport to Laguardia Airport via Washington Dulles
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 27m
- Frequency
- Once daily
- Estimated price
- $270–420
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Buffalo to Boston
- Ave. Duration
- 10h 5m
- Frequency
- Twice daily
- Estimated price
- $85–130
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo to Ithaca
- Ave. Duration
- 3h 45m
- Frequency
- 3 times a day
- Estimated price
- $26–40
- Schedules at
- Flixbus USA
Bus from Ithaca to Boston
- Ave. Duration
- 7h 55m
- Frequency
- 6 times a week
- Estimated price
- $60–90
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
University at Buffalo to Boston bus services, operated by Greyhound USA, arrive at Boston station.
University at Buffalo to Boston train services, operated by Amtrak, arrive at Boston station.
Yes, the driving distance between University at Buffalo to Boston is 452 miles. It takes approximately 7h 52m to drive from University at Buffalo to Boston.
There are 1801+ hotels available in Boston.






