There are 5 ways to get from University at Buffalo to Chicago by plane, train (Amtrak), bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago Midway International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane BUF - MDW
2h 30m$134–473Bus (Greyhound)
cheapest- Take the bus from Buffalo to Cleveland Bus Stationbus Greyhound US0171 / ...
- Take the bus from Cleveland Bus Station to Chicago Bus Stationbus Greyhound US0164
14h 13m$89–179Train (Amtrak)
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain Lake Shore Limited
10h 46m$203–389Drive 538.1 mi
- Drive from University at Buffalo to Chicagocar 538.1 mi
9h 10m$99–142Fly to Chicago O'Hare International Airport
- Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane BUF - ORD
2h 53m$184–413
University at Buffalo to Chicago by foot and bus (Greyhound)
Questions & Answers
The cheapest way to get from University at Buffalo to Chicago is to bus which costs $85 - $180 and takes 14h 13m.
The fastest way to get from University at Buffalo to Chicago is to fly which takes 2h 30m and costs $130 - $480.
No, there is no direct bus from University at Buffalo to Chicago station. However, there are services departing from Flint Circle and arriving at Chicago Bus Station via Main Street & University Station, Buffalo and Cleveland Bus Station. The journey, including transfers, takes approximately 14h 13m.
No, there is no direct train from University at Buffalo station to Chicago station. However, there are services departing from Buffalo Depew Station and arriving at Chicago Union Station via . The journey, including transfers, takes approximately 10h 46m.
The distance between University at Buffalo and Chicago is 489 miles. The road distance is 541.2 miles.
The best way to get from University at Buffalo to Chicago without a car is to train which takes 10h 46m and costs $200 - $390.
It takes approximately 2h 30m to get from University at Buffalo to Chicago, including transfers.
University at Buffalo to Chicago bus services, operated by Greyhound USA, depart from Buffalo station.
University at Buffalo to Chicago train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from University at Buffalo to Chicago is to fly which takes 2h 30m and costs $130 - $480. Alternatively, you can train, which costs $200 - $390 and takes 10h 46m, you could also bus, which costs $85 - $180 and takes 14h 13m.
What companies run services between University at Buffalo, NY, USA and Chicago, IL, USA?
Southwest Airlines and Delta fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW) 5 times a day. Alternatively, Amtrak operates a train from Buffalo Depew Station to Chicago Union Station twice daily. Tickets cost $170–350 and the journey takes 10h 33m.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $75–440
- Website
- united.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $65–380
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $95–470
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $65–380
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $75–440
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $170–350
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
University at Buffalo to Chicago bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
University at Buffalo to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between University at Buffalo to Chicago is 541 miles. It takes approximately 9h 10m to drive from University at Buffalo to Chicago.
There are 1295+ hotels available in Chicago.